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Epidemiol Infect 2001 Dec;127(3):509-16 |
The aetiology of maculopapular rash diseases
in Niteroi, State of Rio de Janeiro, Brazil: implications for measles
surveillance.
Oliveira SA, Siqueira MM, Camacho LA, Nogueira RM, Spinetti CC, Cubel Garcia
RC, Knowles W, Brown DW.
Disciplina de Doencas Infecciosas e Parasitarias, Hospital Universitario
Antonio Pedro, Niteroi, RJ, Brazil.
A study investigating the causes of rash diseases using systematic laboratory
testing was conducted in Niteroi, Rio de Janeiro, between January 1994 to April
1998. Sera from 327 patients were tested for evidence of anti-rubella virus,
measles virus, human parvovirus B19 and dengue fever virus specific
immunoglobulin IgM and anti-human herpes virus type 6 (HHV-6) IgG antibodies. A
laboratory confirmed diagnosis was achieved in 71.3% of the cases investigated:
dengue fever (33.0%), rubella (20.2%), parvovirus B19 (9.2%), measles (6.7%)
and HHV-6 (2.1%). No diagnosis was established for 94 cases (28.7%). An
outbreak of measles was detected during 1997, with a peak in September and
October. All of the diseases studied here presented with clinical features
similar to measles and classical symptoms were found in all measles confirmed
cases. The large overlap of combinations of signs and symptoms seen in this
study highlights the difficulties of diagnosing a rash illness on clinical
grounds alone.
PMID: 11811885 [PubMed - indexed for MEDLINE]
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