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‘When
there are 20 or 30 estimates, we’ll have a better measure of how well it’s
truly working.’
—
DR. KARIN GALIL
Lead
author of the study |
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DR. KARIN GALIL,
lead author of the study in Thursday’s New England Journal of Medicine, and
other experts said it is much too early to propose such a change.
“When there are 20 or 30 estimates, we’ll have a better measure of
how well it’s truly working,” said Galil, who was an epidemiologist for the
Centers for Disease Control and Prevention when she studied the outbreak and
now works for a company developing a new antibiotic.
Seven earlier studies found the vaccine protected at least 71 percent
of the children who got shots from developing the disease and kept the
disease minor in nearly all those infected by the virus. |
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But the latest study tracked by far the worst performance of a
vaccine that has cut the number of U.S. chicken pox cases by 80 percent
since it was introduced in 1995.
The outbreak was at a day care center near Concord, N.H. A boy who
had been vaccinated three years earlier came down with the virus on Dec. 1,
2000. By Jan. 11, 2001, it had spread to 24 other children — including 17
who also had been vaccinated.
New Hampshire does not require chicken pox vaccinations. About
two-thirds of the children had been vaccinated; six of the seven
unvaccinated children in the boy’s class got sick.
VACCINE LIMITS SEVERITY OF
ILLNESS |
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The vaccine did keep the illness
minor, Galil said. One boy was diagnosed with a single blister and developed
only two more after that.
In addition, there is evidence the vaccine protects against shingles,
a painful skin and nerve infection that strikes decades after chicken pox.
The ailment’s lack of virulence makes it hard to tell how the vaccine
is working, said Dr. Harry Keyserling, a pediatrics professor at Emory
University School of Medicine and chairman of the Georgia Department of
Human Resources’ Vaccine Registry Advisory Committee. |
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“The problem
with breakthrough chicken pox is it’s generally so mild that no one would
seek medical attention,” he said. “So unless an organized study is done to
look at breakthrough disease after five or 10 years of vaccinations, we
won’t have the data that we need to make those types of decisions.”
Keyserling, who was not involved in the study, said the most
important finding was that children vaccinated at least three years before
being exposed were more likely to get chicken pox than those who had more
recent inoculations.
© 2002 Associated Press. All rights reserved. This material may
not be published, broadcast, rewritten or redistributed.
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