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http://www.ivanhoe.com/channels/p_channelstory.cfm?storyid=5032

Reported December 25, 2002

Prostate Cancer Vaccine

DURHAM, N.C. (Ivanhoe Newswire) --


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Men experiencing prostate cancer must also endure the side effects of treatment. These can often cause more mental anguish than the disease itself. But now a new treatment could stop prostate cancer without the side effects.

 

Bob Anderson is one of those prostate cancer patients that has to battle the side effects of treatments like chemotherapy. "In addition to killing the cancer cells, it also kills your red blood cells and your white blood cells," Anderson tells Ivanhoe.

And often chemotherapy kills energy. Anderson used to play tennis, ski and hike. He says, "All of those things were impacted to the point where I just am not able to participate in them anymore."

Now a new vaccine could eliminate those draining side effects Anderson experienced. To create the new vaccine, researchers from Duke University Medical Center in Durham, N.C., removed immune cells from cancer patients. Then they sensitized them to the cancer and re-injected them into the patients' bloodstream. There, the immune cells activated other immune cells to attack.

Duke researcher Johannes Vieweg, M.D. tells Ivanhoe, "The miracle is that these cells only attack cancer cells, but not normal cells, so I think we have a very specific and targeted therapy which has no side effects whatsoever."

He says the vaccine may not eliminate prostate cancer altogether, but may keep it from spreading.

"In the next decade I think we will find improvements to these strategies and completely tackle the cancer puzzle and hopefully can cure patients in the future," says Dr. Vieweg.

Just the prospect for an easier treatment is enough for Anderson. He says, "Even if it only lasted for a short period of time and didn't actually cure the cancer, but allowed my body to recover, would allow me to maintain a reasonable lifestyle."

Though Duke researchers have found the vaccine to be safe, more testing is needed to determine just how effective it is in fighting prostate and other forms of cancer.

If you would like more information, please contact:

Amy Austell
Duke University Medical Center News Office
382 Hanes House
DUMC 3354
Durham, NC 27710
(919) 684-4148
amy.austell@duke.edu

 

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