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Image: Smallpox Vaccination At Naval Medical Center  
Hospital Corpsman 2nd Class Jeremy West gives the smallpox vaccine to a member of a military emergency response team on Friday.
1-in-3 troops ineligible for
smallpox shots
Soldiers exempted due
to health conditions

NBC NEWS AND NEWS SERVICES
    Dec. 19 —  A week after a smallpox vaccination program for military troops began, one in three soldiers has been exempted from the mandatory shots because of medical complications. The situation underscores the importance of careful screening and public education about smallpox, yet a new poll finds that a majority of Americans still knows little about the disease or the vaccine.  


 

     
     
       
   
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The most common medical exemptions were for skin conditions, such as eczema.

 
       IN THE first five days of the smallpox vaccination program, 276 people have been screened for the vaccine, with 102 — 37 percent — exempted for medical conditions, said Dr. William Winkenwerder Jr., assistant secretary of defense for health affairs. The others received the inoculation.
       Nearly half of those exempted live with someone who would be at risk for a side effect. The vaccine is made with a live virus, and it can escape the inoculation site and infect people who come into close contact with the person vaccinated.
       The most common medical exemptions were for skin conditions, such as eczema. People with skin conditions are at increased risk for serious side effects from the vaccine.
       
NO SERIOUS COMPLICATIONS
       So far, there have been no serious complications among those inoculated, and Winkenwerder is hoping that careful screening will mean far fewer problems than were found in the smallpox program in the 1960s. During that time, there were one or two deaths for every million people vaccinated and at least 15 life-threatening complications per million.
       “We’re paying a whole lot more attention to screening,” he said.
       The vaccinations began last Friday, targeting about 500 people who would serve on smallpox response teams. In the next stage, beginning in January, the Pentagon will vaccinate about 25,000 medical teams in hospitals and large clinics across the country, and up to 500,000 overseas troops in high-risk areas, particularly southwest Asia.
 
 
 
 
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       To help educate those receiving the shots, officials are busy preparing detailed information about the smallpox vaccine and its risks, including graphic photographs.
       “I think, realistically, a picture is worth a thousand words,” said Dr. Julie Gerberding, director of the federal Centers for Disease Control and Prevention.
       But she added that people will also be told that the risk of these complications is quite low, particularly for people who do not have skin conditions, compromised immune systems or other risk factors.

 
 
 
 
       
       
AMERICANS ILL-INFORMED
       A new survey published on the New England Journal of Medicine’s Web site highlights the need for education about both the disease and the vaccine. Routine inoculations ended in 1972 and the last natural case of smallpox occurred in 1977. Americans know little about smallpox today, despite many months of news reports and discussion about the possibility of a bioterrorist release of the virus.
       “It’s staggering,” said Robert J. Blendon, who directed the survey at the Harvard School of Public Health.
       Blendon’s survey was based on calls to 1,006 randomly selected adults over the past two months. It carried a sampling error of plus or minus 3 percentage points.
       Among the findings:
* 30 percent of Americans believe there has been a smallpox case in the United States in the past five years, and 63 percent think there has been one somewhere in the world. Actually the last U.S. case was in 1949, and the last in the world was in 1977.
* 25 percent said death from the vaccine was likely. The actual death rate from the shots is estimated to be less than three per million.
* 78 percent said they thought medical treatment for smallpox would prevent death or serious illness. Actually, there is no proven treatment after symptoms start.
* Only 16 percent think the country has enough vaccine to give everyone in case of a smallpox attack. The government says it has enough for all.
* 58 percent do not believe that vaccination within a few days of exposure will prevent people from contracting smallpox. Actually, it will.
       
BIOTERROR SCENARIOS
       Meanwhile, the Bush administration’s policy of providing smallpox vaccinations to doctors and nurses, but not the general population, was supported by a detailed study released Thursday. The analysis examined various scenarios of a smallpox attack and concluded that the number of deaths in an outbreak would range from as few as 19 to as many as 55,000, depending on the nature of the attack.
 
  BIOTERRORISM; complete coverage

 
 
       The study, which was published in the New England Journal of Medicine and sponsored by the RAND Center for Domestic and International Health Security, said smallpox could be spread by terrorists in various ways, resulting in widely divergent numbers of deaths.
       One scenario would be to let three smallpox-infected terrorists ride mass transit in a large city. The researchers estimated that fewer than 20 people would die before the disease was contained through a vaccination campaign.
       The worst scenario imagined was turning 40 terrorists loose on a busy day in 10 large airports with portable nebulizers spraying smallpox into the air. Unless most of the population had already been vaccinated, between about 40,000 and 55,000 people would die.
       The study also found that while mass vaccinations ahead of an actual bioterror attack may not be warranted, it is important for health workers to be vaccinated, as President Bush’s policy has ordered.

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       For instance, if 60 percent of all 288 million Americans were vaccinated, the result would be nearly 500 deaths from the vaccine, even if smallpox never reappears. However, in an outbreak, health care workers are the ones most likely to catch the virus. They make up 3 percent of the population but would account for 20 percent to 60 percent of all smallpox cases, depending on which scenario of disease spread is used.
       “We show there would be a net benefit to vaccinating health workers, even if there is a low probability of an attack, because health workers are at greatly increased risk,” said the study’s director, Dr. Samuel Bozzette of the Veterans Affairs San Diego Healthcare System.
       Jim Bentley, a senior vice president of the American Hospital Association, said most hospitals seem willing to participate in the effort to vaccinate health care workers, others are deliberating, and a few have indicated they do not want their staff vaccinated.
       Among the reluctant facilities are Grady Memorial Hospital in Atlanta and Virginia Commonwealth University’s health center in Richmond, Va.
       The American Medical Association has endorsed the concept of voluntary vaccinations for health care workers but says it will monitor the program for possible complications.
       HHS has launched a Web site for people with questions about smallpox and the president’s vaccination plan to visit for information.
 
 
 
 
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       The Associated Press and Reuters contributed to this report.
       

 
 
     
       
   
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Vaccination News Home Page

ALL INFORMATION, DATA, AND MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE IS FOR GENERAL INFORMATION PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS REFLECTING THE KNOWLEDGE OR OPINIONS OF THE PUBLISHER, AND IS NOT TO BE CONSTRUED OR INTENDED AS PROVIDING MEDICAL OR LEGAL ADVICE.  THE DECISION WHETHER OR NOT TO VACCINATE IS AN IMPORTANT AND COMPLEX ISSUE AND SHOULD BE MADE BY YOU, AND YOU ALONE, IN CONSULTATION WITH YOUR HEALTH CARE PROVIDER.