http://news.independent.co.uk/uk/health/story.jsp?story=110688
Senior Government advisers sought to head off a
potential public health scare yesterday after two people with the human form of
BSE were found to have shared the same batch of polio vaccine.
Although the two victims of variant
Creutzfeldt-Jakob disease (vCJD) both took the oral form of the vaccine, made
using bovine blood, scientists believe the cases are a coincidence.
Professor Peter Smith, chairman of the Spongiform
Encephalopathy Advisory Committee (Seac), revealed that an investigation by
scientists has failed to find evidence of a link between other cases of vCJD
and the polio vaccine.
However, Seac scientists are concerned that even
raising the possibility of a link could turn parents away from childhood
immunisation programmes, which have already suffered bad publicity over alleged
health risks.Deidre Cunningham, a public health specialist and new member of
Seac, said: "An absolutely infinitesimal risk was absolutely no
justification for ruining a vaccination and immunisation programme that
actually does protect people's health."
The two vCJD patients are part of a group of five
"geographically-associated cases" in the Southampton area. Both were
given oral polio vaccine from a batch distributed in 1994, six years before the
vaccine was banned. Each batch consisted of between 70,000 and 80,000 doses and
was part of a larger consignment of about five million doses each made by an
identical process of growing the vaccine in blood serum drawn from foetal
calves.
The Department of Health recalled the vaccine in
October 2000 because it breached European guidelines banning the use of foetal
calf serum from countries affected by BSE.
However, a comparison of patients with vCJD and
healthy people failed to find evidence to suggest that the vaccine could have
caused the transfer of BSE from cattle to humans.
Professor Smith said: "Looking at the cases as
a whole, there is really nothing to implicate polio vaccine [as a source of
vCJD]." Both patients lived in the Southampton area, were of a similar age
and could have shared many other features of their lifestyle. Both received the
polio vaccine as young adults.
"It's highly likely that they would have had
polio vaccine from the same batch – that's why we didn't attribute any
particular significance to this," he said.
Ray Bradley, a veterinary scientist and member of
Seac, said tests had failed to find any evidence that BSE could be transmitted
in the blood of adult cattle, let alone foetuses. "Foetal calf serum is
used in most viral vaccines and there have been millions of vaccines prepared
in this manner and no evidence whatsoever [of] any transmission of BSE."
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