MEDSCAPE's Pediatrics MedPulse 12-07-01

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MedPulse is a weekly index of key news and features on Medscape's

specialty sites compiled by Medscape's Editors.

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___________________ NEW FEATURE ARTICLES THIS WEEK ____________________

ASK THE EXPERTS - DOSE OF HEPATITIS B VACCINE

Until recently, children under 11 who were not exposed to hepatitis B were

given 2.5 mcg of vaccine. Subsequently, a recommendation was made to give a

higher dose (the dose previously reserved for infants born to Hep B

antigen-positive mothers). What is the evidence that this higher dose for

children not at immediate risk is necessary?

http://pediatrics.medscape.com/45812.rhtml?srcmp=ped-120701

<a href="http://pediatrics.medscape.com/45812.rhtml?srcmp=ped-120701"> Read

it Here</a>

ASK THE EXPERTS - VACCINE OVERLOAD?

Is there a danger of "immunological fatigue" with so many vaccines being

recommended, ie, can the immune system go on responding to an indefinite

number of antigens?

http://pediatrics.medscape.com/45813.rhtml?srcmp=ped-120701

<a href="http://pediatrics.medscape.com/45813.rhtml?srcmp=ped-120701"> Read

it Here</a>

ASK THE EXPERTS - FORMULATION OF THE US IMMUNIZATION SCHEDULE

What are the factors that determine the inclusion of a vaccine into the

United States immunization schedule?

http://pediatrics.medscape.com/45815.rhtml?srcmp=ped-120701

<a href="http://pediatrics.medscape.com/45815.rhtml?srcmp=ped-120701"> Read

it Here</a>

CURRENT ADULT AND PEDIATRIC VACCINE RECOMMENDATIONS

Each year in the United States, approximately 50,000 adults die of

influenza, pneumococcal infections, and hepatitis B, and 500 children die

of vaccine-preventable diseases.

http://pediatrics.medscape.com/45749.rhtml?srcmp=ped-120701

<a href="http://pediatrics.medscape.com/45749.rhtml?srcmp=ped-120701"> Read

it Here</a>

VACCINES IN THE 21ST CENTURY

vaccination is regarded as the most effective strategy for preventing

infectious diseases.

http://pediatrics.medscape.com/45748.rhtml?srcmp=ped-120701

<a href="http://pediatrics.medscape.com/45748.rhtml?srcmp=ped-120701"> Read

it Here</a>

VACCINES IN THE PIPELINE -- AN OVERVIEW

For a number of diseases that remain significant public health challenges

throughout the United States and the rest of the world, vaccines have yet

to be developed or made available.

http://pediatrics.medscape.com/45751.rhtml?srcmp=ped-120701

<a href="http://pediatrics.medscape.com/45751.rhtml?srcmp=ped-120701"> Read

it Here</a>

JOURNAL SCAN - PEDIATRICS 4(10)

Journal Scan is the clinician's guide to the latest clinical research

findings in Pediatrics, The Journal of Pediatrics, Archives of Pediatrics

and Adolescent Medicine, Pediatric Infectious Disease Journal.

http://pediatrics.medscape.com/45799.rhtml?srcmp=ped-120701

<a href="http://pediatrics.medscape.com/45799.rhtml?srcmp=ped-120701"> Read

it Here</a>

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___________________________________ NEWS ______________________________

MOTHER'S WEIGHT IS THE MAIN LINK BETWEEN OFFSPRING'S BIRTHWEIGHT AND ADULT WEIGHT

Maternal weight appears to explain most of the association between

birthweight and adult body mass index, and may be a more important risk

factor for childhood obesity than birthweight.

http://pediatrics.medscape.com/45920.rhtml?srcmp=ped-120701

<a href="http://pediatrics.medscape.com/45920.rhtml?srcmp=ped-120701"> Read

it Here</a>

INFANTS BORN AT NIGHT OR EARLY MORNING ARE AT INCREASED RISK OF EARLY DEATH

Infants born at night or early morning, particularly around the time of

hospital shift changes, have a greater mortality risk compared with infants

born during the day.

http://pediatrics.medscape.com/45919.rhtml?srcmp=ped-120701

<a href="http://pediatrics.medscape.com/45919.rhtml?srcmp=ped-120701"> Read

it Here</a>

INFANTS WITH RECURRENT WHEEZE HAVE ALTERED LUNG FUNCTION

Recurrent wheeze in infants is related more to alterations in respiratory

tissue mechanics than to airway mechanisms or forced volumes.

http://pediatrics.medscape.com/45675.rhtml?srcmp=ped-120701

<a href="http://pediatrics.medscape.com/45675.rhtml?srcmp=ped-120701"> Read

it Here</a>

EARLY TWO-DOSE MEASLES VACCINATION DEEMED USEFUL IN ENDEMIC AREAS

An early two-dose measles vaccination schedule can improve vaccination

coverage in areas at high risk of measles among infants.

http://pediatrics.medscape.com/45778.rhtml?srcmp=ped-120701

<a href="http://pediatrics.medscape.com/45778.rhtml?srcmp=ped-120701"> Read

it Here</a>

FLUCONAZOLE PROPHYLAXIS PREVENTS FUNGAL INFECTIONS IN PRETERM INFANTS

When given during the first 6 weeks of life, fluconazole effectively

prevents fungal colonization and invasive fungal infections in extremely

low-birthweight infants.

http://pediatrics.medscape.com/45847.rhtml?srcmp=ped-120701

<a href="http://pediatrics.medscape.com/45847.rhtml?srcmp=ped-120701"> Read

it Here</a>

PROACTIVE SCREENING AND TREATMENT RECOMMENDED FOR PRIMARY NOCTURNAL ENURESIS

Physicians need to be proactive in screening and treating school-aged

children for primary nocturnal enuresis.

http://pediatrics.medscape.com/45692.rhtml?srcmp=ped-120701

<a href="http://pediatrics.medscape.com/45692.rhtml?srcmp=ped-120701"> Read

it Here</a>

CHILDHOOD METHYLPHENIDATE TREATMENT REDUCES ADULT COCAINE RESPONSE

Methylphenidate treatment early in life may blunt the pleasurable effects

of cocaine in adulthood.

http://pediatrics.medscape.com/45876.rhtml?srcmp=ped-120701

<a href="http://pediatrics.medscape.com/45876.rhtml?srcmp=ped-120701"> Read

it Here</a>

SOCIOECONOMIC STATUS AFFECTS RATES OF BLINDNESS

Lower socioeconomic status, whether between or within countries, is

strongly associated with rates of blindness.

http://pediatrics.medscape.com/45688.rhtml?srcmp=ped-120701

<a href="http://pediatrics.medscape.com/45688.rhtml?srcmp=ped-120701"> Read

it Here</a>

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ALL INFORMATION, DATA, AND MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE IS FOR GENERAL INFORMATION PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS REFLECTING THE KNOWLEDGE OR OPINIONS OF THE PUBLISHER, AND IS NOT TO BE CONSTRUED OR INTENDED AS PROVIDING MEDICAL OR LEGAL ADVICE. THE DECISION WHETHER OR NOT TO VACCINATE IS AN IMPORTANT AND COMPLEX ISSUE AND SHOULD BE MADE BY YOU, AND YOU ALONE, IN CONSULTATION WITH YOUR HEALTH CARE PROVIDER.