http://dailynews.yahoo.com/h/nm/20011207/hl/autistic_1.html

 

Friday December 7 5:25 PM ET

Autistic Children at Heightened Risk of Epilepsy

By Joene Hendry

NEW YORK (Reuters Health) - Children with autism appear to have a higher-than-average risk of epilepsy, suggesting that the two share a common brain abnormality, researchers report.

The investigators say that epilepsy should be suspected when an autistic child shows signs of a seizure disorder.

Autism and epilepsy are outwardly very different. Epilepsy is a seizure disorder; autism affects a person's ability to communicate, relate to others and react to his or her environment--although some people with the disorder are high-functioning.

But both are brain-based disorders, and past studies have shown that autism and epilepsy often occur together, with epilepsy seen in up to 30% of people with autism.

``We know there is a higher rate of seizure disorders in autism,'' Dr. John Pomeroy told Reuters Health.

He and his colleagues at State University of New York-Stony Brook reviewed brain-activity recordings called electroencephalograms (EEGs) from 38 children with autism, aged 1 to 15. They found that 14 of these children, or 37%, also had epilepsy.

All but two of these children had seizures or a worsening of their autistic disorder prior to obtaining the EEG results. Those two children were both in the lower-functioning range of autism, which, according to Pomeroy's team, makes it more difficult to recognize possible signs of epilepsy.

Overall, the children with epilepsy were more likely than the other children to have convulsions, ``staring episodes'' or a history of regression--a worsening of autistic symptoms.

Despite their findings, Pomeroy and colleagues caution against conducting routine EEGs in children with autism.

Unless there is evidence a child is having seizures or regression, Pomeroy said, there is rarely epileptic-type activity revealed in the EEG.

Pomeroy's group noted that other behaviors seen in children with autism, such as breath-holding spells and episodes of rage, rarely relate to epilepsy and were not related in any children in this study.

The investigators conclude that the prevalence of epilepsy ''is significantly higher than chance'' in children with autism. However, they add, ``there is little support to perform routine EEG'' in high-functioning autistic children showing no signs of seizure disorders.

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