http://bmj.com/cgi/content/full/325/7360/0/f
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Systematic reviews of randomised controlled trials provide an evidence base
for treatment but too often fail to give adequate information on long
term outcomes, which are important for people with chronic diseases.
Elphick and colleagues (p
381) discuss the limitations of systematic reviews of randomised
controlled trials for patients with chronic diseases and maintain
that long term observational studies have a place in evaluating the
benefits and risks of treatment.
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