MOLECULAR BIOLOGY:
In Yeast, Prions' Killer Image Doesn't Apply
Jennifer Couzin
Infectious proteins called prions have been fingered for
causing an array of rare but horrific brain illnesses. Researchers studying
these misfolded proteins have found prions in yeast and fungus; unlike those in
mammals, however, they don't seem to harm the host. Now a radical new line of
inquiry is casting human prions not as prototypical evildoers but more like the
rare bad guys in an extended family of eccentrics.
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