"Can Mumps Vaccine Induce Remission in Recurrent Respiratory Papilloma?"
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Eleven children with recurrent respiratory
papilloma (RRP) were selected for a trial examining the use of laser excision
and locally injected mumps vaccine to cause remission of the disease. The early
trial employed laser excision alone for one year, while a later study with 18
children and 20 adults employed the laser excision with adjuvant therapy. All
of the patients went through laser excision of papilloma followed by locally
injected mumps vaccine, with remission only declared after two consecutive
disease-free intervals and a follow-up of at least one year, determined by
microphotographs of the larynx and trachea. The study of 11 children resulted
in remission in nine patients, or 82 percent, by 1 to 10 injections, with
follow-up of five years to 19 years. The study of 38 patients showed remission
in 29 of them, or 76 percent, between four injections and 26 injections, with
follow-up of two years to five years. The studies indicate that injection with
mumps vaccine following laser excision is a positive factor in the remission of
RRP in children.
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