Arthus reaction to recombinant hepatitis b virus vaccine.

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11512098&dopt=Abstract

 

Clin Infect Dis 2001 Sep 15;33(6):906-8

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Arthus reaction to recombinant hepatitis b virus vaccine.

Froehlich H, Verma R.

Department of Pediatrics, Kaiser Permanente Medical Center, Fresno, CA, USA. froehlich.h@ghc.org

A severe, local, inflammatory, late-phase reaction accompanied by skin necrosis occurred after an infant was given an intramuscular injection of recombinant hepatitis B virus vaccine. The clinical course and appearance of the rash were typical of an Arthus reaction. Although not identical to this case, prior reported cases of complement-mediated reactions occurring after hepatitis B virus infection or vaccination provide theoretical support for this diagnosis.

PMID: 11512098 [PubMed - in process]

 

 

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