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Clin Infect Dis 2001 Sep 15;33(6):906-8 |
Arthus reaction to recombinant hepatitis b
virus vaccine.
Froehlich H, Verma R.
Department of Pediatrics, Kaiser Permanente Medical Center, Fresno, CA, USA.
froehlich.h@ghc.org
A severe, local, inflammatory, late-phase reaction accompanied by skin necrosis
occurred after an infant was given an intramuscular injection of recombinant
hepatitis B virus vaccine. The clinical course and appearance of the rash were
typical of an Arthus reaction. Although not identical to this case, prior
reported cases of complement-mediated reactions occurring after hepatitis B
virus infection or vaccination provide theoretical support for this diagnosis.
PMID: 11512098 [PubMed - in process]
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