http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11502677&dopt=Abstract

Acute myopericarditis after diphtheria, tetanus, and polio vaccination.

Boccara F, Benhaiem-Sigaux N, Cohen A.

Service de Cardiologie (Drs. Boccara and Cohen), Saint Antoine University and Medical School, Paris.

We report the first case of myopericarditis after triple vaccination against diphtheria, tetanus, and poliovirus in a young adult. He presented with fever, acute chest pain, and diffuse ST-segment elevation 2 days after vaccination. Two-dimensional echocardiography findings were normal. Endomyocardial biopsy showed interstitial edema with diapedesis of erythrocytes. Laboratory findings showed inflammatory syndrome and elevated circulating immune complexes. He recovered within a few days with high-dose aspirin treatment and was without complications at 3-month follow-up. We discuss the different hypotheses for infective or hypersensitivity myocarditis.

PMID: 11502677 [PubMed - in process]

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