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Microbiology

VIROLOGY:
Poliomyelitis Eradication--a Dangerous Endgame

Neal Nathanson and Paul Fine

Efforts to eradicate poliovirus from the face of the Earth have been very successful, thanks in large part to the oral poliovirus vaccine developed by Albert Sabin. However, as Nathanson and Fine explain in their Perspective, maintaining a world free from poliomyelitis will not be easy. They discuss the implications of a recent outbreak of paralytic poliomyelitis on the island of Hispaniola from which wild poliovirus was eliminated 10 years previously (Kew et al.).


N. Nathanson is in the Departments of Microbiology and Neurology, University of Pennsylvania, Philadelphia, PA 19104, USA. E-mail: nathansn@mail.med.upenn.edu P. Fine is at the London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK. E-mail: paul.fine@lshtm.ac.uk

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Nathanson, N. || Fine, P.
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Outbreak of Poliomyelitis in Hispaniola Associated with Circulating Type 1 Vaccine-Derived Poliovirus.
 
Olen Kew, Victoria Morris-Glasgow, Mauricio Landaverde, Cara Burns, Jing Shaw, Zacarías Garib, Jean André, Elizabeth Blackman, C. Jason Freeman, Jaume Jorba, Roland Sutter, Gina Tambini, Linda Venczel, Cristina Pedreira, Fernando Laender, Hiroyuki Shimizu, Tetsuo Yoneyama, Tatsuo Miyamura, Harrie van der Avoort, M. Steven Oberste, David Kilpatrick, Stephen Cochi, Mark Pallansch, and Ciro de Quadros
Science 2002 296: 356-359. (in Reports) [Abstract] [Full Text]  

 


Volume 296, Number 5566, Issue of 12 Apr 2002, pp. 269-270.
Copyright © 2002 by The American Association for the Advancement of Science. All rights reserved.

 

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