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SCHAFER AUTISM REPORT "Healing Autism:
No Finer a Cause
on the Planet"
________________________________________________________________
NOTE: Update November Calendar of Events
is now out:
http://home.doitnow.com/~events
Separate But
Related Vaccine Controversies Erupt in
Amidst a growing threat of measles
epidemics on both sides of the
In addition to these articles, there is
published today on the internet a detailed overview and history of the MMR
Vaccine controversies, concurrent with an Online Autism Conference at the same
location: http://www.redflagsdaily.com.
More details on this are at the end of this posting. -Editor
ON THIMEROSAL VACCINES AND AUTISM
* New Study Disputes Vaccine, Autism Link:
AP
* Mercury-Laced Vaccines A Threat, Child
Group Says:
From
* Autism Groups Dispute Government’s Closed
Use of Vaccine Database
ON MMR VACCINE AND AUTISM
*
* Focus: The Truth About MMR: The
Independent,
* Major Review of MMR Controversy &
Autism Online Conference Today
ON THIMEROSAL VACCINES AND
AUTISM
New Study Disputes Vaccine,
Autism Link
Critics say mercury in shots
led to nervous-system problems
http://www.cnn.com/2003/HEALTH/parenting/11/03/mercury.vaccines.ap/
AP - Government researchers say they
found little evidence of a link between vaccinations and developmental problems
in a study of more than 140,000
The report didn't satisfy vaccine
critics, who claimed the study's initial results showed a stronger connection
but were watered down. They also noted that the study's lead author now works
for a vaccine maker.
The study, published Monday in the
December issue of Pediatrics, is one of the latest attempts to determine
whether older vaccines with the mercury-containing preservative thimerosal led
to nervous-system problems such as autism, as some vocal critics contend.
In one group of children studied, routine
vaccines in infancy appeared to slightly increase the risk for tics. In another
group, a slight association was seen with language delays but not tics. A third
group showed no associations with any disorder.
In all, more than 140,000 children were
studied and no link was found with any other disorders, including autism, said
co-researcher Dr. Frank DeStefano of the Centers for
Disease Control and Prevention.
Many previous studies of vaccines
containing the preservative thimerosal also failed to find strong evidence of
any link.
The new results are reassuring, DeStefano said, and more definitive answers are expected
from in-person examinations the CDC is giving some of the study participants.
Charges of a cover-up But Dr. Mark Geier, a geneticist who has worked as a consultant on
parents' lawsuits against vaccine makers, said the researchers' own earlier
analysis of the study results found strong links between vaccines and such
problems -- and that the published results attempt to conceal those findings.
He claimed the final analysis “is intentional fraud.”
DeStefano
acknowledged that the early results suggested stronger links with some
disorders, though not autism, but denied that there had been pressure or a
cover-up. He said the final data reflect a more thorough recent analysis.
The study's lead author, former CDC
researcher Dr. Thomas Verstraeten, now works for
vaccine maker GlaxoSmithKline in
Verstraeten,
who left the CDC in July 2001, did not respond to an e-mail request seeking a
response, and company spokeswoman Nancy Pekarek said
he did not wish to discuss the results. She provided a written statement in
which Verstraeten indicated that since leaving the
CDC he has worked only as an adviser as the study was finalized and prepared
for publication.
The researchers analyzed data from three
health maintenance organizations on children born between 1992 and 1999 and tracked
for several years. Information was gathered on several neurodevelopmental
disorders, including autism, attention deficit disorders, stammering and
emotional disturbances.
While the researchers were beginning to
examine their results, public health officials were beginning to publicly
address concerns about the use of thimerosal in childhood vaccines.
Preservative no longer used Mercury in
high doses has been linked with neurodevelopmental
problems. Parents and others worried about potentially dangerous overexposure
to thimerosal because of the increasing number of vaccines recommended in
childhood.
Vaccine makers have since phased out use
of thimerosal as a preservative in childhood vaccines used in the
It is still used as a preservative
elsewhere, especially in developing countries, said Dr. Thomas Saari, a member of the
Vaccine expert Dr. Neal Halsey of
“A major health risk should have shown up
in a consistent pattern in all three of the HMOs,” Halsey said.
Still, he said the findings might have
been different if the researchers had done a separate analysis by gender, since
boys are much more susceptible to mercury exposure than girls.
Copyright 2003 The
Associated Press.
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* * *
Mercury-Laced Vaccines A Threat, Child Group Says
[By Cheryl Wetzstein
for The
A vaccine safety study of more than
124,000 babies that appears today [Monday] in the journal Pediatrics concludes
there are “no consistent significant associations” between mercury-laced vaccines
and maladies such as autism or attention-deficit disorder.
However, an advocacy group is accusing
federal researchers of finding such a link in “earlier, secret studies” and
“manipulating data” to cover it up.
“They found the truth and then swept it
under the rug,” said Lyn Redwood, the mother of an autistic child and president
of Safe Minds, a
Mercury is known to have toxic effects on
the brain. Thimerosal, a mercury-containing preservative, was used for decades
to stabilize vaccines. Vaccines today contain little or no thimerosal.
Rep. Dave Weldon, Florida Republican and
a physician, sent a letter Friday to Dr. Julie L. Gerberding,
director of the Centers for Disease Control and Prevention (CDC), asking for a
“thorough, open, timely and independent review” of the study.
“I have reviewed the [Pediatrics] article
and have serious reservations about the four-year evaluation and conclusions of
this study,” Dr. Weldon said.
“While most childhood vaccines now have
only trace amounts of mercury from thimerosal-containing vaccines, it is
critical that we know with certainty if children were injured in the 1990s,” he
wrote.
“I am a strong supporter of childhood
vaccinations, and know that they have saved us from considerable death and
suffering,” he added. However, “[W]e must fully disclose adverse events” to
preserve public confidence in vaccines.
The CDC study, led by Dr. Thomas Verstraeten, was based on vaccine and health data from
124,170 infants born between 1992 and 1999 at two health maintenance
organizations and 16,717 children born between 1991 and 1997 at another HMO.
The researchers found “conflicting
results” about links between vaccines and tics or language delays at different
sites. However, they found no evidence of significant increased risks for
autism or attention-deficit disorder.
Safe Minds leaders say that, according to
materials obtained through the Freedom of Information Act, Dr. Verstraeten said during the early stages of the study that
he thought he saw a “plausible” link between thimerosal-containing vaccines and
autism.
But, “once Dr. Verstraeten
began working for vaccine manufacturer GlaxoSmithKline,
he altered the data, sampling and methodology of the study so that results
would point to enough inconsistencies to cast doubt” on the link, the group
said.
Specifically, they said, CDC researchers
added data from a Massachusetts HMO even though it had data-management problems
and the state is believed to have “severely underreported” its cases of autism.
This data skewed the findings, the Safe Minds leaders said.
Spokesmen for the CDC said Friday they
were reviewing information about these “serious allegations.”
CDC materials say there are no proven
links between autism and vaccines, and American parents and health care workers
should continue to immunize babies and young children against disease.
A spokeswoman at GlaxoSmithKline
referred questions about the study to the CDC, since it was conducted when Dr. Verstraeten was in an agency fellowship program.
GlaxoSmithKline
is named as a defendant in lawsuits filed by persons with autism.
A spokeswoman for the Pediatrics journal
said that the CDC study was “peer-reviewed by multiple experts.” Also, Dr. Verstraeten declared that he was a federal employee and had
no conflict of interest when the study was performed, the journal said.
* * *
Autism Groups Dispute
Government’s Closed Use of Vaccine Database Joint Statement On
Use of the CDC’S Vaccine Safety Datalink For
Thimerosal Investigations
Joint Statement: Vaccine Safety is an
important public health issue.
The Vaccine Safety Datalink
database must be made available to all qualified research scientists in a
timely manner, asserts a collection of major autism organizations. The current practice of restricting access to
the database to a limited group of possibly biased individuals is not
acceptable. This joint statement is
being issued by Apraxia Kids, Autism Research
Institute, Autism Society of America, Cherab
Foundation, Cure Autism Now, Safe Minds, Speechville
Express and Unlocking Autism
Findings drawn from investigations by the
CDC’s National Immunization program using the Vaccine Safety Datalink on thimerosal’s role in Neurodevelopmental Disorders, including the study by Verstraeten et al in Pediatrics (November 2003), cannot be
accepted as final. The Verstraeten et al paper may have methodological and
sampling problems which limit its usefulness. The Vaccine Safety Datalink data must be opened immediately, with a fair and
expedited approval process, to qualified independent researchers, in order to
ensure transparency in scientific research and maintain public trust in the
childhood immunization program.
The November issue of Pediatrics contains
an article by Thomas Verstraeten and colleagues on
the safety of thimerosal-containing vaccines. The study relies on the Vaccine
Safety Datalink (VSD) to examine the association
between exposure during infancy to the mercury preservative thimerosal and
increased risk of developing a neurodevelopmental
disorder (NDD). NDDs include autism, speech/language
delay, attention deficit disorder, and tics. The VSD was established in 1991 to
monitor possible adverse outcomes from vaccines on a post-licensing basis. The
VSD relies on partnering HMOs to provide computerized health records of
children enrolled in their organizations, through which health outcomes can be
linked to vaccine administration. Employees of the CDC National Immunization
Program (NIP), its consultants, and representatives of the HMOs have
periodically issued research papers on vaccine safety using the VSD. The Verstraeten et al study is one of these papers.
The Verstraeten
evaluation of thimerosal and NDDs began 4 years ago,
in the Fall of 1999.
During this time, he and his colleagues completed but never published
three versions of the study plus several sub-analyses. The Pediatrics paper
represents the fourth version. Each study version has produced different
results, due to alterations in the study population or analytic methods used.
The reasons for alterations to the original study protocol have never been
fully explained. The initial version found statistically significant
associations between increased thimerosal exposure and risk of an NDD
diagnosis. It also found an increased
relative risk of 2.48 for autism. According to the original study protocol, a risk higher than 1.5
would be considered a “plausible” association even if not statistically
significant. The second version found a relative risk for autism of
1.69, while the third version did not address autism at all. While the second
version detected a significantly increased risk for speech/language delay,
attention deficit disorder, tics, and neurodevelopmental
delays in general, the third and fourth versions dismissed all associations
between thimerosal and any neurodevelopmental
disorder.
With one recent exception, no other
researchers have been allowed to access the VSD data. Current rules established by NIP make the
approval process for access long and arduous.
Moreover, researchers who gain access can only utilize a limited portion
of the VSD data set, and their examination of the data is subject to constant
monitoring by CDC staff. The single
research group outside of NIP who has gained access to the VSD data for
thimerosal investigation has found significant and large increases in relative
risk for autism and speech/language disorder from thimerosal exposure in DTaP vaccines (study in press).
Situation
Many parents have linked their child’s
autism or other neurodevelopmental disorder (NDD) to
thimerosal in childhood vaccines. Scientific research examining such a link is
being conducted. Public maintenance of trust in vaccine safety is critical for
continued high childhood immunization rates.
Credible research confirming or refuting an association between
thimerosal and NDDs is necessary to maintain public
trust in infant vaccines.
Concerns
The Autism and Speech/Language Disorder
Organizations have concerns about the manner in which the VSD has been used to
investigate the thimerosal issue. The National Immunization Program staff and
its consultants may be perceived as biased in their investigations of the
issue. Lack of true open access to the VSD data by independent researchers
hampers investigation and raises questions as to why such restrictions on the
data are needed when transparency in research is fundamental to maintaining
scientific integrity. Unless the NIP recognizes that the autism community and
the public at large will only accept as valid research that is not only
unbiased but is perceived to be unbiased, these constituencies will never trust
health authorities regarding vaccine safety. Lack of trust puts the
* * *
ON MMR VACCINE AND AUTISM
[By Steve Mitchell for
UPI, from last Friday.] http://www.washtimes.com/upi-breaking/20031031-044151-8440r.htm
UPI - As the
The drop in measles vaccinations also
heightens fears of outbreaks of two other diseases: rubella and mumps. This is
because the measles vaccine generally is administered in conjunction with mumps
and rubella inoculations in a single shot known by the corresponding initials,
MMR. So a drop in measles protection is a drop in rubella and mumps protection
as well.
Of the three diseases, measles carries
the most concern because it is a highly contagious disease with a death rate of
one or two children for every 1,000 infected. It also can cause other serious
complications, including pneumonia, swelling of the brain and seizures.
The major rubella worry is if it infects
women when they are pregnant, then it can cause birth defects in their
developing fetus -- including deafness, eye defects, heart abnormalities and
mental retardation.
“A resurgence in
measles in the
In addition to the expected
Dr. Diane Griffin, chair of the
department of molecular microbiology and immunology at
“There is continued importation of
measles from all these different parts of the world,” including
This prospect concerns health officials
because vaccination rates in some states and cities have dropped to levels that
would allow an outbreak of measles to be sustained if a case gets into the
community. This could have severe consequences as evidenced by measles
outbreaks in the
Vaccination rates in the
In Scottish children under age 15,
suspected cases of measles have jumped by 18 percent in the last 18 months --
and rubella by 22 percent and mumps by 27 percent -- according to statistics
released earlier this week by the National Health Service of Scotland. Most of
these cases will turn out to be due to other causes but the trend does suggest
the diseases are on the increase.
The concern about a widespread outbreak
in the
“There is now unequivocal evidence that
MMR is not a risk factor for autism -- this statement is not spin or medical
conspiracy, but reflects an unprecedented volume of medical study on a
worldwide basis,” Simon Murch, a pediatrician with
the Royal Free and University College Medical School in London, writes in the
Nov. 1 issue of The Lancet.
“Unless vaccine uptake improves rapidly,
major measles epidemics are likely in the (United Kingdom) this winter,” warns Murch who co-authored a 1998 study in The Lancet, along
with Andrew Wakefield -- also of the Royal Free Hospital -- which sparked the
concern the MMR vaccine could cause autism.
The current rate of MMR vaccine coverage
in the
In the
Several areas have rates of only 87
percent or lower, including
Some states have vaccination rates below
the 90 percent mark, including
Keeping the immunization coverage
uniformly high is essential because an increasing number of unvaccinated people
makes it easier for a case of measles to take hold and, in turn, boost the
likelihood of spreading the disease to vaccinated individuals -- because no
vaccine confers 100 percent protection.
“The real threat is the same thing that
has driven down immunization rates in the
In
To make matters worse, “there is concern
among the public health community that parental resistance to vaccines is
increasing” in the
In the
“The potential for introduction into the
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* * *
Focus: The Truth About MMR
[This report is from Saturday. Interviews by Roger Dobson.] http://news.independent.co.uk/uk/health/story.jsp?story=459621
So is the vaccine against measles, mumps
and rubella safe? Yes, says the Government, now backed by one of the scientists
who first raised fears. No, say campaigners who link MMR with autism.
Meanwhile, parents are more bewildered than ever. Paul Vallely
evaluates the claims on both sides - and reveals the new evidence that is yet
to come to court
Confused? If not, you probably haven't
been paying sufficient attention to the debate on the safety of the measles,
mumps and rubella vaccine. Parents who thought they knew what to believe were
bewildered again last week by an announcement from one of the men who first
raised public fears about a possible link between the triple jab and autism. Dr
Simon Murch of the centre for paediatric
gastroenterology at the
Back then, he called for more work to be
done on the MMR. But on Thursday he wrote a letter to The Lancet proclaiming -
in what, to the non-scientific eye, looked like a U-turn - that the MMR was
safe. “There is now unequivocal evidence,” he wrote, “that MMR is not a risk
factor for autism - this statement is not spin or medical conspiracy, but
reflects an unprecedented volume of medical study on a worldwide basis.”
Epidemiological evidence was now overwhelming. Measles epidemics would be
“almost certain” this winter if parents continued to boycott the triple
vaccine, he warned.
Almost immediately, one
of Dr Murch's co-authorscounterattacked.
Dr Andrew Wakefield, who detected virus particles from the measles vaccine in
the bowels of children with autism - and became the scientist who first called
for the MMR to be replaced by three separate vaccines -
attacked the epidemiological studies on the incidence and distribution of
autism as “very flawed”. They had been subject to severe criticism because they
“failed to address the original hypothesis that we put forward”. They had, for
example, lumped all autism together “when in fact
autism can be caused by many things and we may just be looking at a small part
of that autistic spectrum caused by MMR”.
More than that, he suggested that Dr Murch's letter may have been written in response to
intimidation by the medical establishment. Such pressure had been applied to Dr
Wakefield to force him out of his post at the same hospital. “I know he's under
similar pressure from the hierarchy of the Royal Free. His lab is under threat.
He's failed to gain due promotion. He's been strongly advised to withdraw from
scientific publications that involve any mention of my name or association with
the MMR.” All of which was denied by Dr Murch who
insisted: “I have not been leant on at all.” His new view was, he said, based
solely on scientific evidence.
But then came
the most dramatic development. There was now proof of the danger from the MMR,
said Dr Wakefield - and it had not been made public.
“Senior members
of the joint committee on vaccination and immunisation, in their capacity as
expert advisers to the vaccine manufacturers, have been presented with
compelling evidence of a link between MMR and bowel disease in children with
autism,” said Dr Wakefield on Radio 4's Today programme
on Friday. “The situation is a national disgrace,” he added and called for a
public inquiry.
So what is this new evidence? And where
is it? “I'm not in a position to disclose [it] to you,” he said. Murkier and murkier.
The explanation for Dr Wakefield's
reticence lies in a court case. More than 1,000 families who claim that the MMR
was responsible for brain damage suffered by their children are on the brink of
suing the manufacturers of the vaccine. Or, rather, they were.
Dr Wakefield is one of a group of
scientists, mainly in the
Lawyers for the parents are still
reluctant to disclose the new evidence since they are applying - acting without
pay - for a judicial review against the commission's decision. To fund their
activities the families this weekend launched a fighting fund on their website
at www.jabs.org.uk.
What the new evidence is said to reveal
is the most striking link yet between the triple jab and autism. The measles
virus (shown below) has been found in the spinal fluid - and therefore the
brain - in three of the six test case children at the centre of the High Court
battle. By contrast the virus was found in only one of more than 20 control
samples - taken mainly from spinal taps on children with leukaemia.
Parents from the test case wanted to obtain the spinal fluid samples from which
the newest evidence was eventually drawn. But every hospital they approached in
The tests were eventually done. On the
way home, however, the parents were forcefully quizzed by customs officials -
both in the
I have to declare an interest here. My
son has been given separate jabs. There is Crohn's
disease - the bowel disorder implicated by Dr Wakefield - in the family. So we
were not prepared to take any risks. He has had the rubella and the measles
inoculations. We are waiting for the supply of the mumps vaccine to arrive,
though we are not anxious since the big danger from mumps is in puberty.
This highlights part of the dilemma over
vaccines. They do two things; they protect the individual, and they protect the
whole population. The interests of the two are not synonymous.
A small boy does not have much risk from
rubella; the main reason for the jab is to control the disease generally, and
protect those at risk: if a woman contracts rubella
early in pregnancy, there is a 90 per cent chance her baby will suffer mental
and physical defects. Measles, by contrast, is a serious threat to both
individual and the population. With mumps the real risk is to a pubescent youth
or man; vaccinating toddlers is mainly about creating herd immunity, not
individual protection.
What is best for the child and best for
the nation are not therefore completely congruent. Dr Murch's
argument is that the divergent risk is so statistically small that it is as
irrational for a parent to refuse the MMR as it would be to allow their child
in a car or a plane.
But when parents make the risk/benefit
calculation with a vaccine it is not the statistical probability which weighs
with them. Instead they ask why should they take any
risk with their child, especially when the Government argument against single
vaccines is so weak. (It claims many parents will forget to return for the next
jabs and that children are exposed to extra risk in the six-week periods
between jabs.) The problem for the Government ought to be one of balance. It is
undoubtedly best for general public health to force the MMR on everyone. It is
undoubtedly better from the perspective of individuals that they be allowed the
choice of separate jabs. Whatever the science, no one bears the responsibility
for a child's health in the same way as parents.
In a liberal democracy we should expect a
balance to be struck that makes allowance for both these facts, even if the
resulting compromise is not the optimum from an epidemiological point of view.
When, instead, we have an attitude by the authorities that smacks of bullying
and manipulation, the sense of crisis is likely to grow rather than diminish.
My child had rubella. If
everyone had the triple injection, it would die out
Vicky Load, 47, from
If everyone had the MMR, the rubella that
my only child has would die out, and no one else would get it ever again. After
what we have been through, I really wish that could happen. Children really do
need to be protected against this horrible disease which can destroy lives. It
is easy for me to say, but people should have their children vaccinated.
It was a very big shock when we
discovered that Louise, our only child, had rubella when she was born. She has reasonable
sight in her right eye with the help of glasses, but she has a congenital
cataract on the left eye which is very dense. They say it cannot be removed and
that there would be no sight there anyway. As well as her sight problems she
has no hearing at all, and there are problems with her legs and her mobility.
It was dreadful and a real shock to
discover that she had rubella and that she was damaged in such a way. I had no
symptoms, but I think I may have been in contact with someone in the bank where
I worked and that I passed it on to her. I was shocked, but you can't waste
time feeling sorry for yourself. You have got to get on with it.
She is a lovely girl and we love her so
very much. But I passionately believe that people should have the MMR. I think
the message I would give is that everyone should be vaccinated. I know people
are worried about the MMR and autism, but there are other things that people
need to take into account, especially rubella. The fact is that you are at risk
of rubella if you are not vaccinated. That's not a theory: it is the painful
reality.
If the MMR vaccine uptake does not start
to increase soon there is a real risk of outbreaks of rubella, which is
extremely dangerous to unborn children. MMR has been a huge success in reducing
the number of babies born deaf and blind as a result of rubella and as far as I
known there is no scientific evidence of a link with autism.
Before, he was a happy boy,
laughing a lot. He was never the same again
June Cox-Smith says her son Edward came
home a different child after he had the MMR vaccination. He was vaccinated at
the age of 13 months and she says he has never been the same since.
He is six and a half now and he is
severely autistic. He cannot communicate with other people in a normal way.
His speech is very limited; he cannot
talk to people, and his handwriting is limited too, although his intelligence
is high. He has problems with all kinds of communication.
He has no social skills and cannot join
in with other children when they are playing. He also has very little
imagination, although he is very affectionate. Someone told me that being as
autistic as he is is like being dropped on Mars and
not knowing any of the social requirements. You watch people, but you have no
idea what they are doing or why. You have no understanding of what is going on.
We have no doubt that the MMR is to
blame. He had it when he was 13 months old, and he was very sick and he had a
temperature straight away. He was ill for several days, almost two weeks, and
he never recovered his old self. He was never the same boy again.
Before, he was a happy boy, playing with
his brother, laughing a lot. He liked being with other people and joined in
with games, and had good times. He was so very different afterwards. He came
back after the MMR as a completely silent child who didn't smile. It wasn't
until he was four and half that he said anything at all. He was silent, and I
mean really silent. All we had until then were grunts.
We have two older children, and they both
had the MMR with no problems, but Edward has been badly affected. If we had any
more children we most certainly would not expose them to the MMR - no way. We
feel so strongly that we did not let Edward have his booster. We also had
difficulty in getting any real advice. We found that whenever we asked about
the downside of the MMR, they would just start talking about children dying
from measles. We know that the cause of Edward's severe autism is the MMR that
he had, and we very much wish that he had not had it.
* * *
Comprehensive Review of MMR
Controversy and Autism Online Conference Today
From Nicholas Regush,
Editor, Redflagsdaily.com
Friday, a scientific controversy
concerning the MMR (measles, mumps,
rubella) vaccine broke out in the
Dr. Edward Yazbak,
a well-known pediatrician, and a RFD columnist, had prepared a major piece on
the MMR and autism for the online Autism Conference, scheduled to begin at RFD
on November 3.
We decided to publish this extraordinary
investigation by Dr. Yazbak without delay. It is now
posted on the home page at RFD. Everyone interested in vaccines, the practice
of medicine and the manner in which the Medical Establishment conducts itself
should read this entire piece. It is one of the strongest publications ever at
RFD. We strongly recommend it. http://www.redflagsdaily.com
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DISCLAIMER: All information, data, and material contained, presented, or provided here is for general information purposes only and is not to be construed as reflecting the knowledge or opinions of the publisher, and is not to be construed or intended as providing medical or legal advice. The decision whether or not to vaccinate is an important and complex issue and should be made by you, and you alone, in consultation with your health care provider.