National
Desk
| May 28, 2003, Wednesday
Hormone Use
Found to Raise Dementia Risk
By DENISE GRADY (NYT) 1430 words
Late Edition - Final , Section A ,
Page 1 , Column 3
ABSTRACT
- Large study reported in AMA Journal finds
that hormone treatment doubles risk of
Alzheimer's disease and other forms of
dementia in women who began treatment at age
65 or older; latest bad news about hormone
therapy comes from four-year experiment
involving 4,532 women at 39 medical centers,
half taking placebos and half Prempro,
estrogen-progestin combination that is most
widely prescribed form of therapy; 40 cases
of dementia developed after four years in
hormone group and 21 in placebo group; Dr
Sally Shumaker, who directed study for
Women's Health Initiative, says clear
message is that there is no reason for older
women to take combination therapy; Wyeth to
add new caution label (M) Hormone therapy
doubled the risk of Alzheimer's disease and
other types of dementia in women who began
the treatment at age 65 or older, a large
study has found.
The finding disappointed many researchers
and doctors, who had hoped for the opposite
result: that hormone therapy would prevent
Alzheimer's disease.
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