Juvenile sarcoidosis after BCG vaccination

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May 2003, part 2 • Volume 48 • Number 5

 


 

Case Reports
Juvenile sarcoidosis after BCG vaccination

Genevieve E. N. Osborne, MRCP [MEDLINE LOOKUP]
Eleanor Mallon, MRCP [MEDLINE LOOKUP]
Susan C. Mayou, BSc, FRCP [MEDLINE LOOKUP]
London, United Kingdom

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   Abstract  TOP 

We report the case of a 2-year-old boy with juvenile sarcoidosis, in whom the cutaneous lesions first arose at the site of and soon after a BCG vaccination. Juvenile sarcoidosis is rare, and the pattern of clinical features is distinct from the adult form of sarcoidosis, possibly related to immunologic development. The cause of sarcoidosis is unknown, although there is much interest in the possibility of mycobacterial species operating as antigenic stimuli to initiate the disease. This case suggests that the Mycobacterium bovis present in the BGC vaccination may have been etiologically important in the development of sarcoidosis. (J Am Acad Dermatol 2003;48:S99-102.)

 

   Publishing and Reprint Information  TOP 
  • This supplement is made possible through an unrestricted education grant from Stiefel Laboratories to the American Academy of Dermatology.
  • From the Department of Dermatology, Imperial College School of Medicine, Chelsea and Westminster Hospital.
     
  • Reprint requests: Dr G. E. N. Osborne, Specialist Registrar in Dermatology, St John's Institute of Dermatology, St Thomas' Hospital, Lambeth Palace Road, London, SE1 7EH, United Kingdom.
     
  • Copyright © 2003 by the American Academy of Dermatology, Inc.
     
  • 0190-9622/2003/$30.00 + 0
     
  • doi:10.1067/mjd.2003.158


 

 

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