The Global Burden of Measles in the Year 2000A Model that Uses Country-Specific Indicators

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http://www.journals.uchicago.edu/JID/journal/issues/v187nS1/020666/brief/020666.abstract.html

The Journal of Infectious Diseases    2003;187:S8-S14
© World Health Organization 2003. All rights reserved. The World Health Organization has granted the Publisher permission for the reproduction of this article.
0022-1899/2003/18710S-0002

 

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SUPPLEMENT ARTICLE

The Global Burden of Measles in the Year 2000—A Model that Uses Country-Specific Indicators

Claudia E. Stein,1 Maureen Birmingham,2 Mary Kurian,2 Philippe Duclos,2 and Peter Strebel3

1Global Programme on Evidence for Health Policy and 2Vaccines and Biologicals, World Health Organization, Geneva, Switzerland; 3Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, Georgia

 

The estimation of the global burden of measles is challenging in the absence of reliable and comparable surveillance systems worldwide. A static model is described that enables estimation of measles morbidity, mortality, and disability for the year 2000 on the basis of country-specific information (i.e., demographic profile, vaccine coverage, and estimates of case-fatality ratios). This approach estimated a global incidence of 39.9 million measles cases, 777,000 deaths, and 28 million disability-adjusted life years. The World Health Organization regions of Africa and Southeast Asia had 70% of incident cases and 84% of measles-related deaths; 11 countries alone (Afghanistan, Burkina Faso, Democratic Republic of the Congo, Ethiopia, India, Indonesia, Niger, Nigeria, Pakistan, Somalia, Uganda) account for 66% of deaths. This approach quantifies the measles burden by considering country-specific indicators, which can be updated, permitting an assessment of country, regional, and global changes in the burden associated with measles infection.

 


     Presented in part: Child Health Epidemiology Reference Group meeting, convened by WHO, Gex, France, February 2002.
     The views expressed herein are solely those of the authors and are not those of the World Health Organization.

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