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http://www.journals.uchicago.edu/JID/journal/issues/v187nS1/020666/brief/020666.abstract.html
The Journal of Infectious Diseases 2003;187:S8-S14
© World Health Organization 2003. All rights reserved. The World Health
Organization has granted the Publisher permission for the reproduction of this
article.
0022-1899/2003/18710S-0002
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| SUPPLEMENT ARTICLE |
The Global Burden
of Measles in the Year
2000A Model that Uses
Country-Specific Indicators
Claudia E. Stein,1 Maureen Birmingham,2 Mary Kurian,2 Philippe Duclos,2 and Peter Strebel3
1Global
Programme on Evidence for Health
Policy and 2Vaccines and
Biologicals, World Health Organization,
Geneva, Switzerland; 3Global Immunization
Division, Centers for Disease
Control and Prevention, Atlanta,
Georgia
| The estimation of the global burden of measles
is challenging in the absence of reliable and
comparable surveillance systems worldwide. A static
model is described that enables estimation of
measles morbidity, mortality, and disability for the
year 2000 on the basis of country-specific
information (i.e., demographic profile, vaccine
coverage, and estimates of case-fatality ratios).
This approach estimated a global incidence of
39.9 million measles cases, 777,000 deaths, and
28 million disability-adjusted life years. The
World Health Organization regions of Africa
and Southeast Asia had 70% of incident cases
and 84% of measles-related deaths; 11 countries alone
(Afghanistan, Burkina Faso, Democratic Republic of
the Congo, Ethiopia, India, Indonesia, Niger,
Nigeria, Pakistan, Somalia, Uganda) account for 66% of
deaths. This approach quantifies the measles burden
by considering country-specific indicators, which
can be updated, permitting an assessment of
country, regional, and global changes in the
burden associated with measles infection.
|
Presented in part: Child Health Epidemiology
Reference Group meeting, convened by WHO, Gex, France,
February 2002.
The views expressed herein are solely those of the
authors and are not those of the World Health
Organization.
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