Physician Knowledge of Catch-up Regimens and Contraindications for Childhood
Immunizations
Nicole J. Cohen, MD*, Diane S.
Lauderdale, PhD, Priya B. Shete, BA*,
John B. Seal, MA* and Robert S. Daum, MD*
* Pediatric Immunization Program, the Department of Pediatrics
Department of Health Studies, University of Chicago, Chicago, Illinois
Objectives. To determine physician success at designing
catch-upregimens for children delayed in immunizations and physicianknowledge regarding contraindications to immunization.
Methods. A self-administered survey was completed by pediatricians,general practitioners, and family practitioners in Cook County,
Illinois. Surveys included 6 open-ended vignettes describing
hypothetical children delayed in immunization for whom participants
were asked to design catch-up regimens. Bivariate and multivariate
logistic regression were used to determine predictors of correct
response. The surveys also inquired about management of scenarios
that might be perceived as contraindications to immunize withthe
Haemophilus influenzae type b or measles-mumps-rubella vaccines.
Results. The mean score of correct responses was 1.83 of a possible6.0. Almost one third of respondents answered all 6 vignettes
incorrectly. The proportion of incorrect responses was highfor all 6
vignettes (39%86%), but higher for questionsthat addressed the
immunization of children older than 12 months.Errors in vaccine
administration were most commonly attributedto omitted vaccines,
with varicella-zoster vaccine and pneumococcalconjugate vaccine
omitted most frequently. Pediatricians were>4 times more likely to
answer correctly than were familypractitioners. Participants in the
Vaccines for Children (VFC)program were more than twice as likely to
answer correctly thanwere non-VFC providers. Knowledge of
contraindications was inconsistent,particularly for
measles-mumps-rubella vaccine.
Conclusions. Childhood vaccine providers have substantial knowledgedeficits of recommended immunization schedules and vaccine
contraindicationsthat may contribute to missed opportunities to
immunize. Pediatriciansand participants in the VFC program were more
successful atdesigning catch-up regimens for children with
immunization delay.
Abbreviations: AAP, American Academy of Pediatrics ACIP,
Advisory Committee on Immunization Practices VFC, Vaccines for Children AMA,
American Medical Association Hib, Haemophilus influenzae type b MMR,
measles-mumps-rubella HIV, human immunodeficiency virus VZV,
varicella-zoster vaccine DTaP, diphtheria-tetanus-acellular pertussis PCV,
pneumococcal conjugate vaccine IPV, inactivated polio vaccine
Received for publication Jul 19, 2002; accepted Nov 12, 2002.
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"A foolish faith in authority is the worst enemy of truth."
-- Albert Einstein, letter to a friend, 1901
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-- Thomas Jefferson, letter to William C. Jarvis, September 28, 1820
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