As fears of bioterrorism subside and worries about a SARS
pandemic grow, public health officials are retreating from the Bush
administration's ambitious campaign to vaccinate millions of people
for smallpox.
The first stage of the vaccination program, designed to inoculate
smallpox-response teams in every hospital in the country,
effectively flopped: only 33,000 of the intended 450,000 health-care
workers were inoculated.
Tomorrow, an Institute of Medicine advisory panel overseeing the
program will get an update from federal, state and local
public-health officials.
Those officials are now redefining what it means to be "prepared"
for a smallpox attack - while grappling with the more urgent threat
of severe acute respiratory syndrome (SARS), the new virus that has
struck Asia and Canada.
"Right now we are working with each of the states to get a feel
from them about where they think they are in their [smallpox]
preparedness," said Michael Sage, deputy director of terrorism
preparedness at the Centers for Disease Control and Prevention. "It
isn't one answer. It is 50 answers."
In many states, including Pennsylvania and New Jersey, health
officials say the new answer focuses less on numbers and more on the
ability to detect and contain a smallpox outbreak and mobilize
emergency vaccination clinics.
"The success of the program cannot just be measured by numbers,"
said Eddy Bresnitz, New Jersey state epidemiologist.
In the first phase of New Jersey's program, which ended this
month, 657 people were inoculated - 14,400 fewer than the state was
prepared to vaccinate. New Jersey plans to evaluate the program
before continuing, Bresnitz said. Pennsylvania has vaccinated 93 of
a planned 22,500 health-care workers; state health officials say
they still hope to inoculate 4,500 people by midsummer.
Even critics praise the administration and the CDC for
stockpiling enough vaccine to inoculate every American, developing a
system to distribute the vaccine, and training a cadre of
professionals to administer it.
But it's a far cry from the program President Bush billed as a
key part of his strategy against bioterrorism.
Despite the resistance to the first part of the smallpox program,
administration officials say they are going ahead with the second
phase, originally aimed at vaccinating millions of police, health
and emergency workers.
The second phase, many observers believe, will be just as
unpopular as the first.
"I see no reason at all" for more inoculations, said Marilyn
Hostetter, a nurse and officer of SEIU Nurse Alliance, the largest
health-care union in Pennsylvania. "We're advising our members not
to get vaccinated" unless smallpox reappears.
The resistance stems from several concerns. The vaccine has
dangerous, occasionally deadly, side effects (heart inflammation was
added to the list after it occurred in several dozen new vaccinees).
And Congress could not agree until earlier this month on a liability
and compensation plan, which some union leaders say is inadequate.
Finally, there was widespread skepticism about the need for
pre-attack vaccination. There was no proof that Iraq possessed
smallpox, and even if an attack occurred, inoculation days after
exposure to the virus can still ward off the disease.
"I don't like to say, 'I told you so,' but the desire of this
administration to be seen as doing something to protect against
terrorism has led to less than judicious use of resources," said
Nicholas King, a bioterrorism expert at the University of
California, San Francisco.
The government's own smallpox advisory committee initially
recommended pre-attack inoculation of only about 15,000 health-care
workers in selected regional hospitals. The panel noted that
smallpox is not contagious until the pox appear a week or two after
infection, allowing time to identify, quarantine and vaccinate
exposed people - a strategy that helped eradicate smallpox worldwide
by 1980.
All but one panel member - Paul Offit, a vaccine expert at
Children's Hospital of Philadelphia - later endorsed the
administration's more ambitious immunization plan.
Now, even though twice as many people have been vaccinated as the
advisory panel originally recommended, they are far-flung and
uncoordinated.
"Now we have an average of five vaccinated workers per hospital,
so to say we've created... a first line of defense is wrong," Offit
said.
Some observers see parallels between the smallpox campaign and
the swine-flu debacle in 1976.
That year, a new swine flu-type virus infected 500 soldiers at
Fort Dix, killing one - then mysteriously disappeared. President
Gerald R. Ford and his top health officials rejected the idea of
simply developing and stockpiling a new vaccine, and instead ordered
vaccination of all Americans.
The flu did not reappear - and the program was halted after the
new vaccine turned out to cause a rare but sometimes deadly
paralysis.
The driving fear in 1976 was that a deadly flu would ignite an
worldwide pandemic like the one that killed tens of millions in
1918.
Today, the fear is terrorism.
"The administration is fighting Sept. 11 and the anthrax attacks,
during which they were accused of not doing enough to protect the
public," said Robert J. Blendon, a Harvard University professor of
health policy and political.
"But now, the Iraq war is over and [biological weapons] have not
been found yet. So the question is: How great a risk is smallpox? Is
there really a risk? If not, why should I take a risk to be
vaccinated?"