Herpes zoster virus sclerokeratitis and anterior uveitis in a child following varicella vaccination

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Volume
 

135
 

Issue
 

3 (March 2003)
 

Pages
 

415-417
 


 

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Herpes zoster virus sclerokeratitis and anterior uveitis in a child following varicella vaccination

Ayman Naseri a, William V. Good a,b a,b and Emmett T. Cunningham Jr. aA
New York, New York , USA10021; fax: (212) 628-0698.[a]Francis I. Proctor Foundation and Department of Ophthalmology (A.N., E.T.C), University of California at San Francisco Medical Center, San Francisco, California, USA[b]Smith-Kettlewell Eye Research Institute (W.V.G.), San Francisco, California, USA
A Inquiries to Emmett T. Cunningham, Jr., MD, PhD, MPH, Vitreous-Retina-Macula Consultants of New York; 519 East 72nd Street, Suite 203;
Manuscript accepted 26 September 2002;

 


 


 


 


 


 

 

 Abstract
 

 

 

 

 


 


 


 


 


 

 

 Purpose
 

 

 

 

 

To report a case of herpes zoster virus sclerokeratitis with anterior uveitis following vaccination with live attenuated varicella vaccine (Oka strain).

 


 


 


 


 


 

 

 Design
 

 

 

 

 

Case report.

 


 


 


 


 


 

 

 Methods
 

 

 

 

 

The case records of the patient were reviewed retrospectively. Pertinent literature citations were identified using MEDLINE.

 


 


 


 


 


 

 

 Results
 

 

 

 

 

A 9-year-old boy presented with herpes zoster ophthalmicus 3 years following vaccination with live attenuated varicella vaccine (Oka strain). Examination of the affected eye revealed a moderate follicular response on the palpebral conjunctiva, decreased corneal sensation, mildly elevated intraocular pressure, diffuse anterior scleritis with marginal keratitis, and a moderately severe anterior uveitis. Amplified DNA from fluid taken from the base of a cutaneous vesicle produced wild-type varicella zoster virus (VZV) DNA, not Oka strain.

 


 


 


 


 


 

 

 Conclusions
 

 

 

 

 

Herpes zoster virus infection needs to be considered in all patients who present with scleritis, keratitis, or anterior uveitis, regardless of their varicella vaccination status.



 


 

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