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Mar. 10, 2003

AIDS VACCINE: A Successful Failure

BY MICHAEL D. LEMONICK

Scientists have been struggling to create an AIDS vaccine since the mid-1980s, so you would think the failure of the most advanced trial of such an inoculation would leave them seriously depressed. But that wasn't the reaction last week when researchers from VaxGen, a California company, announced that its HIV vaccine was largely ineffective.

They were not exactly celebrating, of course. But according to Harvard AIDS researcher Max Essex, nobody really expected it to work. Indeed, says Essex, although a dozen other vaccines are in early stages of testing, "it's extremely unlikely that...

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