June 23, 2003
ATLANTA (USA TODAY) -- The future of the government's
smallpox-preparedness program may be decided not by the White
House or the Centers for Disease Control and Prevention but by
the nurses, doctors and others who are not lining up for
voluntary vaccinations.
Even before an expert panel advised last week against
expanding the vaccine program beyond the first phase, the
program had slowed to about 100 vaccinations a week. Nearly
38,000 medical and public health workers have been immunized,
far fewer than the 450,000 initially expected in the program's
first phase. In the next phase, the vaccine is to be offered
to police, firefighters and emergency workers, potentially 10
million people.
Thursday's recommendation not to move forward was made by
the Advisory Committee on Immunization Practices, which
provides advice on vaccines to the CDC. The committee cited
concerns about "new and unanticipated safety concerns,"
specifically nearly two dozen cases of myocarditis, a
potentially life-threatening inflammation of the heart muscle,
and pericarditis, a less dangerous inflammation of the heart
lining, that have occurred among recently vaccinated people in
the civilian part of the program. The military has seen nearly
50 such cases among the more than 454,000 military personnel
vaccinated since December.
Many medical experts have not been convinced that the
unknown risk of a smallpox attack is balanced by the known
risk of the vaccine itself, which contains a live virus
similar to smallpox that can cause life-threatening side
effects. Offering it to medically trained people within a
medical setting seemed a manageable risk to many on the
advisory committee, but widening the program dramatically did
not.
"The committee has believed from the beginning that we need
to put safety above and beyond all other concerns," said
committee chairman John Modlin, a professor at Dartmouth
Medical School. A pause in the smallpox program, he said,
"will allow us to buy some time and better understand both
sides of the equation, the safety and the threat."
CDC director Julie Gerberding said in a briefing that there
is no indication that the risk of smallpox has changed since
December, when President Bush announced the policy in
preparation for a possible bioterrorist attack. "We have made
a giant step forward in our preparedness," she said, "but we
are not done yet."
The CDC will balance the committee's advice "with the other
priorities that are necessary to make a sound public health
decision," Gerberding said.
Florida already has moved into the second phase of the
program, and 124 emergency workers have been vaccinated. No
slowdown of the program is planned, health department
spokeswoman Lindsay Hodges said. The state "is committed to
this, as both an effort to deter any attack or to react in the
face of an attack," she said.
But in Texas, a decision to wait before moving into Phase 2
"will play well," health department spokesman Doug McBride
said. "There has been concern expressed by state officials for
several months about the wisdom of going straight from Phase 1
into Phase 2 without the time to look at safety
considerations, to assess, to gear up and plan it."
Copyright 2003 USA TODAY, a division of Gannett Co. Inc.