Human Infection Due to
Recombinant VacciniaRabies Glycoprotein Virus
Charles E. Rupprecht,
V.M.D., Ph.D., Leonard Blass, M.D., Kathy Smith, D.V.M., Lillian A. Orciari,
M.S., Michael Niezgoda, M.S., Sylvia G. Whitfield, M.S., Robert V. Gibbons,
M.D., Marta Guerra, D.V.M., Ph.D., and Cathleen A. Hanlon, V.M.D., Ph.D.
Rabies is a fatal viral disease transmitted from animals to
humans. It causes more than 35,000 human deaths per year.1 Successfulapplication of veterinary vaccines can eliminate canine rabies
in an area, but control of rabies in free-ranging carnivoresrequires
other strategies, such as oral vaccination.2 Live viral
vaccines containing modified live rabies or recombinant vacciniarabiesglycoprotein virus, placed in a bait, are used for disease controlin Europe and North America.2,3,4,5 In the United States, morethan 22 million doses of vacciniarabies glycoproteinvaccine
were distributed from 1990 to 2000, . . . (Click here for the
full text of this article.)
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