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Kodak devises a promising tool for
diagnosing hyperactivity
ROCHESTER, N.Y. (AP) — Exploring whether
photographic images can help soothe stress led
Eastman Kodak to a chance finding: A man who
exhibited erratic temperature changes turned out
to have attention deficit hyperactivity disorder.
The discovery five years ago
culminated this spring with Kodak donating seven patents
to a Massachusetts research hospital in hopes of
developing a new tool for identifying the
neurobehavioral disorder that afflicts millions of
Americans.
"The diagnosis of ADHD is highly
subjective — there's no definitive test you can give
someone that says they've got it or they don't," said
Greg Foust, a research manager in Kodak's System
Concepts Center. "What this technology allowed us to do
was not only definitively and objectively determine if
someone had it but also get a sense of the degree of the
affliction."
Kodak scientists spied the
unusual temperature oscillations in one of 72 volunteers
in a 1998 study. The researchers were just starting to
examine whether images, sounds and other distractions
are useful in reducing stress levels or even treating
psychiatric ailments such as depression.
Each volunteer, wearing
headphones to block out sounds, was placed in an empty
room or in front of a blank computer or television for
10 minutes and had temperature sensors attached to their
pinky fingers.
Deprived of visual and audio
stimulation, ADHD sufferers typically become stressed as
they look for an outlet, Foust said. That stress drives
changes in fingertip temperatures that appear to
fluctuate differently from non-ADHD patients, he said.
"The way their temperature
changed was very erratic," Foust said. "It would tend to
decline or rise in a manner that was very bouncy versus,
in non-ADHD persons, the temperature change was very
slow without a lot of oscillation."
Two other people who displayed
"jagged changes" in temperature readings also were found
to be stricken with ADHD.
The disorder affects as many as
10 million adults in the United States and between 4%
and 12% of school-age children — as many as 3.8 million
youngsters. Its symptoms include short attention span,
impulsive behavior, difficulty focusing and sitting
still.
Kodak did a follow-up trial in
2000 on 32 children — half of them diagnosed by doctors
with ADHD — and found its method to be at least 84%
accurate in spotting the disorder. The current diagnosis
process is largely subjective because patients must be
observed over long periods of time, often in both home
and school settings.
In exchange for an $8 million tax
benefit in this year's first quarter, Kodak turned over
its patented procedures to McLean Hospital in Belmont,
Mass., a pioneer in ADHD research affiliated with
Harvard Medical School. Kodak spokesman Anthony Sanzio
said the hospital is much better suited to advance the
research.
If the technology leads to a
commercial product, the hospital will reap all the
revenues.
"These inventions could help lay
the foundation for improving the speed and accuracy of
ADHD tests," said Dr. Martin Teicher, who runs the
hospital's development biopsychiatry research program.
Experts not affiliated with Kodak
or McLean cautioned that much more research is needed.
Dr. Mark Wolraich, professor of pediatrics at the
University of Oklahoma Health Sciences Center,
questioned how well the temperature process can
distinguish "those with an anxiety disorder from those
with ADHD."
Teicher said he doesn't think the
Kodak method "should be construed as a stand-alone test.
It just adds some science to something that tends to be
right now very much an art."
Kodak, the world's biggest
photography company, is still testing whether images can
help alleviate psychological problems. But the results
of its work remain under wraps.
Copyright 2003 The Associated Press. All rights
reserved. This material may not be published,
broadcast, rewritten or redistributed.
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