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http://pmj.bmjjournals.com/cgi/content/abstract/79/931/272
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Postgraduate Medical Journal 2003;79:272-278
© 2003 Fellowship of
Postgraduate Medicine
BEST PRACTICE |
Correspondence to:
Dr Wren Hoskyns, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW,
UK;
debra.delbridge@uhl-tr.nhs.uk
ABSTRACT
Children are important in the epidemiology of tuberculosis as a
marker of recent disease transmission and a reservoir for the future.
Once infected they have a higher risk of progressing to tuberculous
disease. Chest radiography and tuberculin testing with or without
tissue for culture are still the standard tools for confirming the
diagnosis once this is considered. Well researched treatment
protocols are available but multidrug resistant tuberculosis and
coexistent HIV are a challenge. Ensuring compliance with treatment is
a major concern. Controversy still surrounds the place of BCG.
Advances in the molecular genetics of tuberculosis hold out the
possibility of better vaccines.
Keywords: tuberculosis; childhood tuberculosis; tuberculin; BCG
Abbreviations: DOT, directly observed therapy; TU, tuberculin unit
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Copyright © 2003 The Fellowship of Postgraduate Medicine.
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