|
|
|
|
Toxicological Profile
Information Sheet
Background
By Congressional mandate, the Agency for Toxic Substances and
Disease Registry (ATSDR) produces "toxicological profiles" for
hazardous substances found at National Priorities List (NPL) sites.
These hazardous substances are ranked based on frequency of
occurrence at NPL sites, toxicity, and potential for human exposure.
Toxicological profiles are developed from a priority list of 275
substances. ATSDR also prepares toxicological profiles for the
Department of Defense (DOD) and the Department of Energy (DOE) on
substances related to federal sites.
So far, 269 toxicological profiles have been published or are
under development as "finals" or "drafts for public comment"; 244
profiles were published as finals; 99 profiles have been updated.
Currently, 16 profiles are being revised based on public comments
received and 9 profile are being developed as public comment draft.
These profiles cover more than 250 substances.
Toxicological profiles are developed in two stages:
(1) DRAFTS: The toxicological profiles are first produced
as drafts. ATSDR announces in the Federal Register the
release of these draft profiles for a 90-day public comment period.
Request draft toxicological profiles from ATSDR's Division of
Toxicology.
(2) FINALS: After the 90-day comment period, ATSDR
considers incorporating all comments into the documents. ATSDR
finalizes the profiles and the National Technical Information
Service (NTIS) distributes them.
ATSDR's toxicological mailing list
Congress requires ATSDR (1) to provide toxicological profiles to
state health and environmental agencies and (2) to make them
available to other interested parties. The Division of Toxicology
(DT) has a mailing list, which is updated and verified yearly, of
groups and individuals who get free copies of both draft and final
profiles; these include health professionals at federal, state, and
local levels; academicians; nonprofit/environmental groups; members
of the public involved with Superfund sites; and parties with
special needs (considered case-by-case).
If you don't qualify for free copies, you may request final
profiles from NTIS for a fee.
How to contact NTIS
NTIS distributes finalized toxicological profiles for a fee. For
more information, contact:
National Technical Information Service 
5285 Port Royal Road
Springfield, Virginia 22161
1-800-553-6847 or 703-605-6000
NTIS Web Site:
http://www.ntis.gov
ATSDR ToxProfiles 2003™ CD-ROM
The toxicological profiles are also available as a complete
set on CD-ROM. To request a copy call the ATSDR Information
Center at 1-888-422-8737 or email at
atsdric@cdc.gov.
For more information on tox profiles or chemical-specific fact
sheets (ToxFAQs™)
DT Docket: Phone 404-498-0720; Fax 404-498-0093
For more information, write
Division of Toxicology, Agency for Toxic Substances and
Disease Registry
1600 Clifton Road, Mailstop E-29, Atlanta, GA 30333
Phone 404-498-0160 ; Fax 404-498-0094
For more information 24 hours/day
You may call the ATSDR toll free number at 1-888-42-ATSDR
(1-888-422-8737) to get 24-hour recorded information about
Division of Toxicology programs. This phone number includes
options to be transferred to ATSDR personnel for technical
assistance.
ATSDR Internet home page via World Wide Web is
http://www.atsdr.cdc.gov
The profile, public health statements, ToxFAQs™ and other
information are available on the Internet.
FINALIZED TOXICOLOGICAL
PROFILES
NTIS order number is in parenthesis.
Updates are in bold.
Asterisks (*) denote profiles funded by the Department of
Defense.
-A-
-B-
-C-
-D-
-
4,4'-DDT, DDE,DDD (Update) (PB2003-100137)
-
Diazinon (PB/97/121107/AS)
-
Dibenzo(a,h)anthracene (PB/90/247636/AS)
-
Dibromochloropropane (PB/93/110906/AS)
-
1,2-Dibromoethane (PB/93/110740/AS)
-
1,4-Dichlorobenzene (Update) (PB/99/121972)
-
3,3'-Dichlorobenzidine (Update) (PB/99/121980)
-
1,1-Dichloroethane (PB/91/180539/AS)
-
1,2-Dichloroethane (Update) (PB/2001/109103/AS)
-
1,1-Dichloroethene (Update) (PB/95/100152/AS)
-
cis-,
trans- 1,2-Dichloroethene
(Update)(PB/97/121081/AS)
-
2,4-Dichlorophenol (PB/93/110757/AS)
-
1,2-Dichloropropane (PB/90/182122/AS)
-
1,3-Dichloropropene (PB/93/110765/AS)
-
Dichlorvos (PB/98/101124/AS)
-
Di(2-ethylhexyl)phthalate (Update)
(PB2003-100138)
-
Diethyl phthalate (PB/95/264214/AS) *
-
Diisopropylmethylphosphonate (PB/99/102535/AS) *
-
Di-n-butyl phthalate (Update) (PB/2001/109104/AS)
-
1,3-Dinitrobenzene/1,3,5-Trinitrobenzene
(PB/95/264289/AS)*
-
Dinitrocresols (PB/95/264321)
-
Dinitrophenols (PB/95/264339)
-
2,4-
& 2,6-Dinitrotoluene (Update) (PB/99/122004)
-
Di-n-octylphthalate (PB/98/101033/AS) *
-
Dioxin (Update) See Chlorinated
Dibenzo-p-dioxins
-
1,2-Diphenylhydrazine (PB/91/180356/AS)
-
Disulfoton (PB/95/264347)
-E-
-F-
-G-
None Available
-H-
-I-
-J-
-K-
None Available
-L-
-
Lead
(Update) (PB/99/166704)
-M-
-N-
-O-
-P-
-
Pentachlorophenol (Update) (PB/2001/109106/AS)
-
Phenol (Update) (PB/99/122012)
-
Plutonium (PB/91/180406/AS)
-
Polybrominated biphenyls (PB/95/264388)
-
Polychlorinated biphenyls: Aroclors -1260,-1254,
-1248, -1242, -1232, -1221, and -1016 (Update)
(PB/2000/108027)
-
Polycyclic aromatic hydrocarbons: Acenaphthene,
Acenaphthylene, Anthracene, Benzo(a)anthracene,
Benzo(a)pyrene, Benzo(b)fluoranthene, Benzo(g,h,i)perylene,
Benzo(k)fluoranthene, Chrysene, Dibenzo(a,h)anthracene,
Fluoranthene, Fluorene, Indeno(1,2,3-cd)pyrene, Phenanthrene,
Pyrene (Update) (PB/95/264370)
-
Pyridine (PB/93/110831/AS)
-Q-
None Available
-R-
-S-
-T-
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin (PB/89/214522/AS)
-
1,1,2,2-Tetrachloroethane (Update)
(PB/97/121099/AS)
-
Tetrachloroethylene (Update) (PB/98/101181/AS)
-
Tetryl (PB/95/264271/AS) *
-
Thallium (PB/93/110856/AS)
-
Thorium (PB/91/180448/AS)
-
Tin
(PB/93/110864/AS)
-
Titanium tetrachloride (PB/98/101082/AS) *
-
Toluene (Update) (PB/2000/108028)
-
Toxaphene (Update) (PB/97/121057/AS)
-
Total Petroleum Hydrocarbons (PB/99/163370) *
-
1,1,1-Trichloroethane (Update) (PB/95/264396)
-
1,1,2-Trichloroethane (PB/90/196411/AS)
-
Trichloroethylene (Update) (PB/98/101165/AS)
-
2,4,6-Trichlorophenol (PB/91/181545/AS)
-
1,2,3-Trichloropropane (PB/93/110872/AS)
-
2,4,6-Trinitrotoluene (PB/95/264297/AS) *
-U-
-V-
-W-
-X-
-Y-
None Available
-Z-
-
Zinc
(Update) (PB/95/100236/AS)
DRAFT TOXICOLOGICAL
PROFILES
Toxicological profiles under development as "draft for public
comment" --
CERCLA Set 15
Atrazine
Fluorides
(Update)
Malathion
Mustard gas
(Update)
Pyrethrins and Pyrethroids
Selenium
(Update)
The public comment period has
ended and the profiles will be revised based on relevant public
comments.
Toxicological profiles under development as "draft for public
comment" --
CERCLA Set 16
Ammonia
(Update)
Chlorine
dioxide
Copper
(Update)
Polybrominated biphenyls/polybrominated diphenyl
ethers (Update)
Synthetic
Vitreous Fibers
The public comment period has ended and the profiles will be
revised based on relevant public comments.
* The toxicological
profile for perchlorates is on a modified
schedule.
Toxicological profiles
under development as "draft for public
comment" --
CERCLA Set 17
Bromoform (Update)
Carbon tetrachloride (Update)
Hexachlorocyclohexanes (Update)
Naphthalene (Update)
Nickel (Update)
Tin (Update)
Tungsten
Zinc (Update)
The CERCLA Set 17 profiles will be made available for public
comment on or about October 17, 2003.
U.S. Department of Energy
toxicological profiles under development as "draft for public
comment" --
DOE Set 2
Americium
Cesium
Cobalt
(Update)
Iodine
Strontium
The public comment period has ended and the
profiles will be revised on relevant public comments.
Editor's note: CERCLA is the Comprehensive Environmental
Response, Compensation, and Liability Act of 1980 (Superfund).
List updated on June 10, 2003
|
