- Home
- Mission Statement
- Daily Vaccine News
- Daily News Archive
- Sandy's Column
- Sandy, Other
- Adverse Reactions
- Age of Autism - UPI
- Archived Sections
- Blogs
- Books
- Contact
- Donate
- Hilary and Ginger
- Important Notices
- Medical Journals
- Other Websites
- Political Action
- Privacy Statement
- RedFlags Archive
- State Laws
- Testimonials
- Unconventional Wisdom
- Vaccination Council
- Vaccines, Pipeline
- Videos
- Video Archive
Provocation poliomyelitis: vaccine associated paralytic poliomyelitis related to a rectal abscess in an infant
>
Return to Vaccination News Home Page __» Right-click to "open in new window" Subscribe to the Vaccination NewsLetter View past & current Scandals (columns by Sandy Mintz) Search This Site using keywords
Journal of Infection
Case ReportProvocation poliomyelitis: vaccine associated paralytic poliomyelitis related to a rectal abscess in an infant A. R. J. Bosley a Department of Paediatrics, North Devon District Hospital, Raleigh Park, Barnstaple, North Devon, UK b Department of Microbiology, North Devon District Hospital, Raleigh Park, Barnstaple, North Devon, UK c Department of Surgery, North Devon District Hospital, Raleigh Park, Barnstaple, North Devon, UK Accepted 12 January 2003. ; Available online 29 March 2003. AbstractObjective. To describe a case of vaccine associated paralytic poliomyelitis (VAPP) and relate this to current UK immunization policy. Method. A case report in which the clinical course and factors leading to the diagnosis are described and then related to reports of paralytic poliomyelitis in the literature. Results. The child in this case was left severely disabled by paralytic poliomyelitis. The pathological process was related to a pararectal abscess needing urgent drainage shortly after immunisation. Conclusion. The skeletal muscle damage due to the presence of the pararectal abscess may have acted as the `provocation' in the development of poliomyelitis. Adoption of a policy of initial vaccination by the parenteral route as in the USA and European countries has been shown to greatly reduce this risk. The UK could adopt this policy which would minimise the risk of VAPP, as all recorded paralytic poliomyelitis in the UK in the last decade has been vaccine related. Author Keywords: Poliomyelitis; Vaccine associated;
Paralytic; Provocation; Immunisation policy
References1. F. Freiderich, Neurologic complications associated with oral poliovirus vaccine and genomic variability of the vaccine strains after multiplication in humans. Acta Virol 42 (1998), pp. 187–195. 2. B.M. Nkowane, S.G.F. Wassilak, W.A. Orenstein et al., Vaccine-associated paralytic poliomyelitis. JAMA 257 (1987), pp. 1335–1340. 3. R. Joce, D. Wood, D. Brown and N. Begg, Paralytic poliomyelitis in England and Wales. BMJ 305 (1992), pp. 69–70. 4. M. Gromier and E. Wimmer, Mechanism of injury-provoked poliomyelitis. J Virol 72 (1998), pp. 5056–5060. 5. S. Mahadevan, S. Ananthakrihnan, S. Srinivasan et al., Poliomyelitis: 20 years––the Pondicherry experience. J Trop Med Hyg 92 (1989), pp. 416–421. 6. P.M. Strebel, N. Ion-Nedelcu, A.L. Baughman, R.W. Sutter and S.L. Cochi, Intramuscular injections within 30 days of immunization with oral poliovirus vaccine––a risk factor for vaccine associated paralytic poliomyelitis. N EJM 332 (1995), pp. 500–506. 7. H.V. Wyatt, Provocation of poliomyelitis by multiple injections. Trans R Soc Trop Med Hyg 79 (1985), pp. 355–358. 8. H.V. Wyatt, Provocation poliomyelitis and entry of poliovirus to the CNS. Med Hypothesis 2 (1976), pp. 269–274. 9. D.M. Salisbury and N.T. Begg, Editors, 1996 Immunisation against Infectious Disease, HMSO, London (1996), p. 26. 10. D.M. Salisbury and N.T. Begg, Editors, 1996 Immunisation against Infectious Disease, HMSO, London (1996), p. 20. 11. A. Finn and F. Bell, Polio vaccine: is it time for a change?.
Arch Dis Child 78 (1998), pp. 571–574.
 Corresponding author. Tel.:
+44-1271-322397; fax: +44-1271-311707
Return to Vaccination News Home Page __» Right-click to "open in new window" DISCLAIMER: All information, data, and material contained, presented, or provided here is for general information purposes only and is not to be construed as reflecting the knowledge or opinions of the publisher, and is not to be construed or intended as providing medical or legal advice. The decision whether or not to vaccinate is an important and complex issue and should be made by you, and you alone, in consultation with your health care provider.
DISCLAIMER: All information, data, and material contained, presented, or provided here is for general information purposes only and is not to be construed as reflecting the knowledge or opinions of the publisher, and is not to be construed or intended as providing medical or legal advice. The decision whether or not to vaccinate is an important and complex issue and should be made by you, and you alone, in consultation with your health care provider.
Copyright 2012 by Vaccination News, A Non-Profit Corporation. All Rights Reserved. This content may not be copied unless permission in writing from Sandy Gottstein has been obtained. 
|
 "A foolish faith in authority is the worst enemy of truth." -- Albert Einstein, letter to a friend, 1901 "I know of no safe depository of the ultimate powers of the society but the people themselves, and if we think them not enlightened enough to exercise control with a wholesome discretion, the remedy is not to take it from them, but to inform their discretion by education." -- Thomas Jefferson, letter to William C. Jarvis, September 28, 1820 "What's the point of vaccination if it doesn't protect you from the unvaccinated?" -- Sandy Gottstein "Who gets to decide what the greater good is and how many will be sacrificed to it?" -- Sandy Gottstein |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Cite
or link using doi