Sepsis treatment: one size does not fit all

Severe sepsis and septic shock are life threatening consequences of infections and are the leading causes of death in intensive care units. On page 262 Bochud and Calandra discuss the epidemiology, origins, and treatment of sepsis, which occurs when immune response to invasive pathogens is poor. Gram negative, Gram positive, and fungal infections account for the most cases, and over the past decades little impact has been made in reducing mortality. Future treatment possibilities include pathogen specific regimens, rather than "one size fits all" strategies.

© 2003 BMJ Publishing Group Ltd

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