Health & Fitness
| January 14, 2003,
Tuesday PERSONAL HEALTH; Scientists Plot Tactics to Outmaneuver Cystic
Fibrosis Gene
By JANE E. BRODY (NYT)
1274 words
Late Edition - Final ,
Section F , Page 5 , Column 2
ABSTRACT
- Jane E Brody column on efforts
to fight cystic fibrosis, disease that afflicts about 30,000 Americans;
notes cystic fibrosis, result of defective protein, is chronic, progressive
and ultimately fatal disease that clogs lungs and pancrease with thick,
sticky mucus; drawing (M) More than 10 million people in this country carry
in all their cells one copy of a defective gene that regulates the movement
of sodium, chloride and water in and out of cells.
These people are, on the surface, perfectly healthy. But when two such
carriers of this defective gene have children, they have a 25 percent chance
that each child will inherit an abnormal gene from each parent and will be
born with cystic fibrosis.
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