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http://query.nytimes.com/gst/abstract.html?res=F30A14FB3E550C778DDDA80894DB404482

Health & Fitness | January 14, 2003, Tuesday
PERSONAL HEALTH; Scientists Plot Tactics to Outmaneuver Cystic Fibrosis Gene

By JANE E. BRODY (NYT) 1274 words
Late Edition - Final , Section F , Page 5 , Column 2

ABSTRACT - Jane E Brody column on efforts to fight cystic fibrosis, disease that afflicts about 30,000 Americans; notes cystic fibrosis, result of defective protein, is chronic, progressive and ultimately fatal disease that clogs lungs and pancrease with thick, sticky mucus; drawing (M) More than 10 million people in this country carry in all their cells one copy of a defective gene that regulates the movement of sodium, chloride and water in and out of cells.

These people are, on the surface, perfectly healthy. But when two such carriers of this defective gene have children, they have a 25 percent chance that each child will inherit an abnormal gene from each parent and will be born with cystic fibrosis.



 

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