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GlaxoSmithKline’s PEDIARIX now Available Nationwide

New Interactive Website Provides Parents With the Immunization Tools They Need

RESEARCH TRIANGLE PARK, NC -- (INTERNET WIRE) -- 01/09/2003 -- GlaxoSmithKline announced today that its pediatric combination vaccine, PEDIARIX(TM) [Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Hepatitis B (Recombinant) and Inactivated Poliovirus Vaccine Combined], is now available. PEDIARIX, approved by the U.S. Food and Drug Administration in December 2002, is the first U.S.-licensed vaccine to offer protection against five serious diseases simultaneously, reducing the total number of shots infants receive by up to six. With more than four million births every year in this country, the use of PEDIARIX could spare infants as many as 24 million injections per year. The company also launched www.PEDIARIX.com, a website dedicated to providing parents with information on childhood vaccines.

“GlaxoSmithKline is proud to be the first company in the United States to offer a single vaccine that provides protection against five serious childhood diseases,” said Barbara Howe, M.D., vice president, Clinical Research and Development and Medical Affairs, Vaccines North America, GlaxoSmithKline. “We were encouraged by the excitement expressed by so many in the medical community last month when PEDIARIX was approved. We anticipate a successful launch as people begin to realize and experience the advantages PEDIARIX offers.”

The current childhood immunization schedule calls for approximately twenty injections in the first two years of life and, with the development and introduction of new vaccines, that number will continue to increase. By reducing the number of shots, combination vaccines help facilitate the addition of new immunizations into the crowded pediatric immunization schedule, help reduce costs for parents and physicians and may reduce the number of office visits.

 

Highlighted Links
www.pediarix.com
 

In fact, the Advisory Committee on Immunization Practices (ACIP), the American Academy of Pediatrics (AAP) and the American Academy of Family Physicians (AAFP) prefer the use of licensed combination vaccines versus separate injections of their equivalent component vaccines. This preference is based on the rationale that the use of combination vaccines is a practical way to overcome the constraints of multiple injections. These groups have stated that, to minimize the number of injections children receive, parenteral combination vaccines should be used, if licensed and indicated for the patient’s age, instead of their equivalent component vaccines.

Nine injections for the primary series are currently recommended to protect infants against diphtheria, tetanus, pertussis (whooping cough), hepatitis B and polio. The use of PEDIARIX will require only three shots to achieve this protection at 2, 4 and 6 months of age.* PEDIARIX has been proven safe and effective in numerous clinical trials, where 20,739 doses of PEDIARIX were administered to 7,028 infants.

PEDIARIX.com: Helping Parents Make Sense of Immunizations

To help educate parents about the diseases their children should be protected against and about the importance of childhood vaccination, GlaxoSmithKline has launched a new website, www.PEDIARIX.com. This interactive educational website provides parents with the tools they need to prepare for their child’s healthcare professional visit, including an immunization schedule, doctor’s office checklist, benefits of combination vaccines, and a backgrounder on the diseases against which childhood vaccinations protect. Healthcare professionals are encouraged to direct parents to www.PEDIARIX.com as a way to help eliminate parental anxiety and confusion about immunizations.

In clinical studies, adverse events in infants receiving PEDIARIX included injection-site reactions (pain, redness, or swelling), fever, and fussiness. Administration of PEDIARIX was associated with higher rates of fever relative to separately administered vaccines (see Adverse Reactions section of the package insert). PEDIARIX is contraindicated in infants with known hypersensitivity to any component of the vaccine including yeast, neomycin, and polymyxin B. As with any vaccine, vaccination with PEDIARIX may not protect 100% of susceptible individuals.

GlaxoSmithKline: A Leader in Vaccines

GlaxoSmithKline, with U.S. operations in Philadelphia, PA and Research Triangle Park, NC, is one of the world's leading research-based pharmaceutical and healthcare companies and is committed to improving the quality of human life by enabling people to do more, feel better and live longer.

For more information on PEDIARIX, please visit www.PEDIARIX.com or call toll-free at 1-866-PEDIARIX (1-866-733-4274).

* See complete prescribing information for indication.

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Contact: Ramona DuBose
Phone: 919-483-2839

 


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ALL INFORMATION, DATA, AND MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE IS FOR GENERAL INFORMATION PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS REFLECTING THE KNOWLEDGE OR OPINIONS OF THE PUBLISHER, AND IS NOT TO BE CONSTRUED OR INTENDED AS PROVIDING MEDICAL OR LEGAL ADVICE.  THE DECISION WHETHER OR NOT TO VACCINATE IS AN IMPORTANT AND COMPLEX ISSUE AND SHOULD BE MADE BY YOU, AND YOU ALONE, IN CONSULTATION WITH YOUR HEALTH CARE PROVIDER.