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Pregnant women and nursing mothers should sharply limit--or even
cease--eating French fries, potato chips or other foods that contain the
chemical acrylamide, according to study released Tuesday by German
researchers.
The researchers said they issued the warning for pregnant women and
nursing mothers because fetuses and newborn babies are particularly
susceptible to the potential harmful effects of acrylamide, a possible
carcinogen. The results of the study were to be broadcast nationwide
Tuesday evening on a German television news program.
The leader of the study, Prof. Fritz Soergel of the Institute for
Biomedical and Pharmaceutical Research in Nuremberg, said that
acrylamide is highly water-soluble. Therefore, fetuses and infants are
more at risk than adults because of their generally higher body water
levels. Furthermore, blood brain barriers in fetuses and newborn infants
are not full developed, meaning that nerve-damaging acrylamide would be
more likely to reach their young brains and cause damage.
Acrylamide first received global attention in April 2002 when Swedish
researchers reported finding the chemical in fried and oven-baked foods,
especially in potato chips and French fries. The findings were at first
greeted with skepticism, but scientists in other nations have since
produced similar results.
High levels of acrylamide have been found to cause cancer in rodents.
Last September the US Food and Drug Administration (
news -
web sites) announced a plan to reduce or eliminate concentrations of
acrylamide in potato and cereal products.
In Germany in the last few months, the potential health threat from
acrylamide has become a major national issue, with Soergel gaining a
reputation as an expert.
Soergel recommends that nursing mothers cease eating all potato
chips, French fries or other potatoes fried in oil at temperatures over
180 degrees centigrade at least until the newborn baby reaches two
months old. He believes pregnant woman should limit acrylamide
consumption to no more than 20 micrograms per day, which he says would
be the equivalent of about 10 grams of potato chips.
In an interview with Reuters Health, Soergel described acrylamide as
a neurotoxic agent that he believes can cause cancer in humans. Soergel
said that he and two colleagues--Prof. Rainer Weissenbacher, of the
University of Munich, and Prof. Edgar Schoemig, of the University of
Cologne--conducted their study during the past six weeks.
They used mass spectrometry to measure levels of acrylamide in the
bodies of pregnant women and in the placentas after they gave birth, and
also in nursing mothers and their breast milk.
Soergel said that tests showed anywhere from 10% to 50% of the
acrylamide levels found in pregnant women was transferred via blood
through the placenta to the fetus.
In breast milk, test showed up to 18.8 micrograms per liter of
acrylamide, he said, adding that if a newborn baby drinks slightly over
half a liter per day it would be consuming nearly 10 micrograms of
acrylamide.
Soergel told Reuters that his team tested breast milk from only two
nursing mothers and from the placentas of three women after they gave
birth. However, he insisted that despite the small sample, the research
team's main findings--that acrylamide can pass from a woman to a fetus
and to a newborn through breast milk--remain valid.
"We wanted to very quickly have an idea," he said. "There is no doubt
about these findings. It is so clear. The basic results will not be
contradicted."
That said, he did concede that with a larger sample in the future,
researchers will be able to more accurately determine levels of
acrylamide that can pass through the placenta or into breast milk.
Soergel emphasized that non-fried potatoes, such as baked or boiled,
are extremely healthy and should not be avoided by pregnant woman or
nursing mothers. Potatoes fried at temperatures "substantially lower"
than 180 degrees centigrade would have only very low levels of
acrylamide and would therefore be safe to eat, he said. When pressed
what temperature would meet his "substantially lower" requirements, he
said 140 degrees.
"What I want to avoid is that mothers avoid potatoes altogether," he
said.
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