Vaccination News Home Page                                            subscribe Vaccination NewsLetter

http://query.nytimes.com/gst/abstract.html?res=F50C17FD3D5C0C728FDDA80894DB404482

National Desk | January 31, 2003, Friday
Treatment Found for 2 Heart Ailments

By SANDRA BLAKESLEE (NYT) 1034 words
Late Edition - Final , Section A , Page 25 , Column 4

ABSTRACT - Scripps Research Institute reports finding way to treat two deadly heart ailments caused by protein that folds into abnormal shape, with implications for treating Alzheimer's, Parkinson's and some twenty other diseases also caused by misfolded proteins; clinical tests planned on patients with familial amyloid cardiomyopathy, which afflicts million blacks, and senile systemic amyloidosis, which clogs heart tissue of 10-15 percent of people over age 80; Dr Jeffrey W Kelly explains treatment with 'small molecule' drug that stops misfolding of transthyretin protein (M) For the first time, researchers have found a way to treat two deadly heart ailments that are caused by a protein that folds into an abnormal shape.

Although the treatment is tailored to the two forms of heart disease, it is based on principles that may lead to similar therapies for other conditions caused by misfolded proteins, including Alzheimer's disease, Parkinson's disease, adult-onset diabetes and the human form of mad cow disease.



 

PURCHASING FROM NYTIMES.COM IS QUICK AND SECURE.
To read the complete article, simply click on one of the BUY NOW buttons below.

You can buy this single article or, for even greater value, you can purchase this article as part of a multi-pack. You'll then have the opportunity to buy additional articles now or in the future at significant savings!
 
Purchase Single Article -- $2.95  
Purchase as part of Article 4-Pack -- $7.95
($1.99/article - a 33% savings!)
Pack expires after 1 month
 		  
Purchase as part of Article 10-Pack -- $15.95
($1.60/ article - a 46% savings!)
Pack expires after 3 months
 		  
Purchase as part of Article 25-Pack -- $25.95
($1.05/ article - a 65% savings!)
Pack expires after 6 months
 		  

How multi-packs work: A multi-pack is an archive package that saves you money by allowing you to pre-purchase a set number of articles in bulk at a reduced price. You can then debit from your multi-pack and quickly access articles from the archive at your convenience over the lifetime of the multi-pack.

Once you purchase an article, you may view it as often as you like over the next 90 days. Archive articles do not include photos, charts or graphics



 


 

 

Expect the World every morning with home delivery of The New York Times newspaper. Click Here for 50% off.


 



Copyright 2003 The New York Times Company | Privacy Information

 

 

Vaccination News Home Page

ALL INFORMATION, DATA, AND MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE IS FOR GENERAL INFORMATION PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS REFLECTING THE KNOWLEDGE OR OPINIONS OF THE PUBLISHER, AND IS NOT TO BE CONSTRUED OR INTENDED AS PROVIDING MEDICAL OR LEGAL ADVICE.  THE DECISION WHETHER OR NOT TO VACCINATE IS AN IMPORTANT AND COMPLEX ISSUE AND SHOULD BE MADE BY YOU, AND YOU ALONE, IN CONSULTATION WITH YOUR HEALTH CARE PROVIDER.