ABSTRACT - Scripps Research Institute reports finding way to treat two deadly heart ailments caused by protein that folds into abnormal shape, with implications for treating Alzheimer's, Parkinson's and some twenty other diseases also caused by misfolded proteins; clinical tests planned on patients with familial amyloid cardiomyopathy, which afflicts million blacks, and senile systemic amyloidosis, which clogs heart tissue of 10-15 percent of people over age 80; Dr Jeffrey W Kelly explains treatment with 'small molecule' drug that stops misfolding of transthyretin protein (M) For the first time, researchers have found a way to treat two deadly heart ailments that are caused by a protein that folds into an abnormal shape.

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