Top scientist warns of "sickness" in US health system
Tim Radford Denver
The US health system is itself sick and needs a national commission to get it
back on the road to recovery, Floyd Bloom, president of the American Association
for the Advancement of Science, told the associations annual meeting last week.
Dr Bloom is the head of neuropharmacology at the Scripps Research Institute,
La Jolla, California. He was editor in chief, until 2000, of the journal
Science, and he once headed the neuropharmacology laboratory at the National
Institutes of Health. That an architect of modern neuroscience chose to open the
largest single public science conference in the United States to make his point
suggests more than just a cautionary diagnosis.
Dr Bloom warned of soaring health premiums, shortages of expertise in a
number of specialties, paperwork burdens, and archaic methods of information
management. And he had more immediate problems in mind. "The threat of war and
the imposition of mass casualties from any new acts of terrorism could prove
calamitous for the US medical communitys ability to care for the ill," he said.
He listed specific problems. Communication was difficult. The number of drugs
available to treat an increasingly elderly population had passed the 10 000
mark. Many of these drugs had covert interactions between them. Patients were
seeing several doctors, who did not know about each other and who were
prescribing drugs that may be mutually antagonistic or toxic.
"So there is a great need for stepping back from this crisis situation and
finding ways to re-examine the decisions that we have made and the choices that
we have in the future," he said. "Unless we do something now, all of the
doubling of the NIHs [National Institutes of Health] research resources . . .
will have a difficult time making it through the pipeline to reach the bedsides
of the patients," he said. Genomic research was unlikely to provide any dramatic
benefits for many years, but it distracted from the problems multiplying right
now.
He also raised the problems that stress in infancy might impose in later life
for millions of Americans. "Stress is the name we give to a natural reaction our
bodies generate when we encounter a situation that is unbeknownst to us," he
said. "We activate our autonomic nervous system, and as a result our blood
pressure goes up, our heart rate goes up, our blood glucose goes up, and our
blood lipids go up. All of which is a great advantage if you are trying to flee
from a threatening situation.
"But if stress is maintained, what results is a change in our metabolism
which permanently results in hyperglycaemia, down-regulation of insulin
receptors, deposits of lipids from those high lipids in the bloods into the
endothelial cells of the capillaries. And prolonged stress of itself is a major
factor in the onset of type 2 diabetes, hypertension, cardiovascular illness,
and various problems of modern society."
He then turned his attention to what he described as the "reactive" health
system in the United States.
"We wait until somebody is sick, and then we try to do something about it.
Preventive medicine has a great deal to offer. Socioeconomic status has
important proclivities for a host of illnesses in our country, including
osteoarthritis. The lower you are in the socioeconomic status scale, the more
likely you are to have osteoarthritis, or asthma, or other kinds of pulmonary
illnesses," he said.
"We cant declare poverty to be gone. But we can recognise what the factors
are and try to apply what we have todayinstead of waiting for molecular
discoveries to tell us how we might tailor drugs at some point in the future."
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