Pharmaceutical industry is main influence in GP prescribing
Roger Dobson, Abergavenny
GPs rely heavily on information provided by the pharmaceutical industry and
its representatives when they prescribe newdrugs.
They are more likely to rely on data provided by drug companies than on
independent sources, the results of a new study haveshown.
"The significant first stage in the decision-making process is awareness of a
new drug. The most important sources were thepharmaceutical
industry, in particular the company representative,non-peer reviewed
literature, the mass media, and, to a lesserextent, hospital
colleagues," said the authors of the study inFamily Practice
(2003; 20:61-8)[Abstract/Free
Full Text].
"Important biomedical influences were the failure of current therapy and
adverse effect profile. More influential than these,however, was the
pharmaceutical representative. Hospital consultantsand observation
of hospital prescribing was cited next most frequently,"the authorswrote.
The report said that, although choosing a medicine for a patient is a key
task for doctors, just why they opt for a particularnew medicine is
often unclear. Many new drugs are not therapeuticinnovations, point
out the authors, but extensions to the rangeof drugs alreadyavailable.
The aim of the study was to look at the factors that influence GPs when they
prescribe a new drug for the first time. Forthe research, 107 GPs
from a mix of 54 high, medium, and low prescribingpractices in two
health authorities in the north west of Englandwere interviewed.
Nineteen new drugs introduced from January 1998to May 1999 were the
focus of thestudy.
According to the results, 92% of the GPs saw representatives, and 70%
regarded them as expedient means of getting drugdata.
"The pharmaceutical industry is the most frequently used information source
and there was an evident association between theevidence distilled
from the representative and prescribing initiation,"said the
authors, from the Prescribing Research Group at the RoyalLiverpool
UniversityHospital.
Although GPs questioned the objectivity of the industry, they generally
considered its information to be factually accurate,albeitselective.
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