Acute encephalitis associated with measles: MRI features
K. Y. Lee1, W. H. Cho1 ,
S. H. Kim1, H. D. Kim2 and I. O. Kim3
(1)
Department of Radiology, Sanggye Paik
Hospital, Inje University, 760-1 Sanggye-7 dong, Nowon-gu Seoul 139707,
Korea
(2)
Department of Paediatrics, Sanggye Paik
Hospital, Inje University, 760-1 Sanggye-7 dong, Nowon-gu Seoul 139707,
Korea
(3)
Department of Radiology, Seoul National
University Hospital, 28, Yongon-dong, Chongno-gu Seoul 110744, Korea
Abstract We document the MRI features
in six patients aged 514 years with acute encephalitis following measles. The
diagnosis was made on a characteristic morbiliform rash and detection of
specific IgM and IgG antibodies. The symptoms of encephalitis occurred
111 days after the appearance of the rash. All patients underwent MRI within
14 days of the onset of neurological symptoms. Diffusion weighted images (DWI)
were obtained in three patients. In all patients, T2-weighted images showed
widely distributed, multifocal high signal in both cerebral hemispheres with
swelling of the cortex, with bilateral, symmetrical involvement of the putamen
and caudate nucleus. The lesions had showed low apparent diffusion
coefficients. Three patients showed subacute gyriform haemorrhage, and
asymmetrical gyriform contrast enhancement on follow-up MRI.
Keywords Brain - Infection - Measles - Magnetic
resonance imaging
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