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Financial Times (www.ft.com)
(04/23/03) P. 23; Brun-Rovet, Marianne
The discovery of the DNA double helix structure
50 years ago was a breakthrough in medical science, and continues to have
ramifications today, though the use of DNA knowledge has thus far been limited
primarily to diagnostic products like medical tests. Few drugs and other
therapeutic treatments have yet to be developed from the information, though
some vaccines have come into the market. The slow pace at which DNA data is
being translated into treatments for disease is understandable, according to
some biotechnology executives, who say that there will undoubtedly be advances
based on DNA research in the future; but skeptics are beginning to suggest that
DNA structure will never have much of an impact on drug design and delivery.
Many of the most celebrated companies working in the DNA field, such as
Cambridge Antibody Technologies, have plenty of products in their development
programs, but have yet to get any drugs to the market despite touting genome
decoding as the way to find drug targets. Vaccine makers Acambis and PowderJect
are benefiting from the genomic information through partnerships with major drug
firms to bring the vaccines to market.
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"A foolish faith in authority is the worst enemy of truth."
-- Albert Einstein, letter to a friend, 1901
"I know of no safe depository of the ultimate powers of the society but the people themselves, and if we think them not enlightened enough to exercise control with a wholesome discretion, the remedy is not to take it from them, but to inform their discretion by education."
-- Thomas Jefferson, letter to William C. Jarvis, September 28, 1820
"What's the point of vaccination if it doesn't protect you from the unvaccinated?"
-- Sandy Gottstein
"Who gets to decide what the greater good is and how many will be sacrificed to it?"