WASHINGTON - A vaccine to prevent the
new mystery disease SARS could be ready for tests on monkeys in
little more than a year, but is still "years away" from human use, a
top federal health official said Monday.
The United States is significantly ramping up efforts to monitor
Severe Acute Respiratory Syndrome, called SARS, in hope of
containing any future U.S. outbreak, and finding drugs that could
treat it and a vaccine to prevent it, top U.S. and international
health experts told a Senate committee Monday.
Health officials cited both hopeful and worrisome signs as the
worldwide case count for the disease soared to 2,608, with 98
deaths, the World Health Organization reported Monday. The United
States has 148 suspected cases and no deaths; only one U.S. victim
has required a ventilator to help breathing, and that person is
improving.
One promising sign is that the likely cause of the killer disease
can grow easily in labs. It is a new member of the coronavirus
family, which includes the virus that causes human colds. Lab
cultivation would allow researchers to test possible treatments for
use in first-generation vaccines, said Dr. Anthony Fauci, director
of the National Institute of Allergy and Infectious Diseases
(NIAID).
Existing animal vaccines for related viruses suggest the same
process can probably be followed for SARS, Fauci said.
However, creating a safe human vaccine is time-consuming. Drug
treatments are likely to be ready before a human SARS vaccine, Fauci
said. Scientists from around the world will meet at NIAID late this
week to coordinate efforts on vaccines and treatments.
Meanwhile, the U.S. Centers for Disease Control and Prevention is
dusting off plans for fighting a super-flu pandemic - such as
shutting down infected hospitals and schools - just in case SARS
gets significantly worse here, CDC Director Dr. Julie Gerberding
told senators.
"There is much more we can do if we need to," Gerberding said.
"We're not at a point where we're anywhere near that."
SARS has hit Asia hardest, starting in the Chinese province of
Guangdong in November, then spreading to Hong Kong, Singapore,
Vietnam and Canada. Gerberding said 140 of the148 U.S. victims had
traveled recently in Asia.
Elsewhere "this disease has spread very rapidly around the world,
and continues to transmit from person to person," said Dr. David
Heymann, director of the World Health Organization's communicable
diseases office.
The Chinese government, after initially denying a problem, is now
cooperating with international efforts to contain SARS from
spreading, he said.
"If these measures had been taken in November, perhaps the
disease would not have spread," Heymann told senators.