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"Oculo-Respiratory Syndrome: a New Influenza Vaccine-Associated Adverse Event?"Immunization Newsbriefs (c) Copyright Information Inc., Bethesda, MD. Brought to you by the National Network for Immunization Information (NNii). Visit NNii's new website at http://www.immunizationinfo.org.
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April 07, 2003
INTERNATIONAL IMMUNIZATION NEWS
"Oculo-Respiratory Syndrome: a New Influenza Vaccine-Associated Adverse Event?" Clinical Infectious Diseases (www.journals.uchicago.edu/CID/home.html) (03/03) Vol. 36, No. 6, P. 705; Skowronski, Danuta M.; Strauss, Barbara; De Serres, Gaston
Doctors in Canada noticed in the winter of 2000-2001 a new adverse event associated with the supply of influenza vaccine from one manufacturer, oculo-respiratory syndrome (ORS). Researchers noted the case definition for ORS includes bilateral conjunctivitis, facial edema, or respiratory symptoms beginning between two hours and 24 hours after influenza vaccination and ending 48 hours after onset of disease. The researchers sought to determine the frequency and severity of the event, contacting 609 patients of an eligible 769 persons through a standardized telephone interview. Of respondents, 13 percent said that they contracted ORS within two hours of vaccination, 27 percent said they experienced symptoms for more than 48 hours, and 42 percent felt that the symptoms they experienced were severe. As a result, the ORS case definition for surveillance for the 2001-2002 influenza vaccination season included onset within 24 hours of vaccination, with no restriction of symptom duration. With this information in mind, the scientists conclude that ORS should be included in annual influenza vaccine safety monitoring programs.
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 "A foolish faith in authority is the worst enemy of truth." -- Albert Einstein, letter to a friend, 1901 "I know of no safe depository of the ultimate powers of the society but the people themselves, and if we think them not enlightened enough to exercise control with a wholesome discretion, the remedy is not to take it from them, but to inform their discretion by education." -- Thomas Jefferson, letter to William C. Jarvis, September 28, 1820 "What's the point of vaccination if it doesn't protect you from the unvaccinated?" -- Sandy Gottstein "Who gets to decide what the greater good is and how many will be sacrificed to it?" -- Sandy Gottstein |