Product Number: T8784
alid 11/1999 - 01/2000
Sigma Chemical Co.
P.O. Box 14508
St. Louis, MO 63178 USA
Tel: 314-771-5765
M A T E R I A L S A F E T Y D A T A S H E E T
SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -
CATALOG #: T8784
NAME: THIMEROSAL SIGMAULTRA
SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -
CAS #: 54-64-8
MF: C9H9HGNAO2S
EC NO: 200-210-4
SYNONYMS
((O-CARBOXYPHENYL)THIO)ETHYLMERCURY SODIUM SALT * ELICIDE * ETHYL(2-
MERCAPTOBENZOATO-S)MERCURY SODIUM SALT * O-(ETHYLMERCURITHIO)BENZOIC
ACID SODIUM SALT * ETHYLMERCURITHIOSALICYLIC ACID SODIUM SALT *
ETHYLMERKURITHIOSALICILAN SODNY (CZECH) * ETHYL (SODIUM O-
MERCAPTOBENZOATO)MERCURY * MERCURATE(1-), ETHYL(2-MERCAPTOBENZOATE(2-)
-O,S)-, SODIUM SALT * MERCUROTHIOLATE * MERCURY, ETHYL(2-
MERCAPTOBENZOATE-S)-, SODIUM SALT * MERFAMIN * MERTHIOLATE *
MERTHIOLATE SODIUM * MERTORGAN * MERZONIN * MERZONIN SODIUM * SET *
SODIUM ETHYLMERCURIC THIOSALICYLATE * SODIUM O-(ETHYLMERCURITHIO)
BENZOATE * SODIUM ETHYLMERCURITHIOSALICYLATE * SODIUM MERTHIOLATE *
THIMEROSAL * THIMEROSALATE * THIOMERSAL * THIOMERSALATE *
SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -
LABEL PRECAUTIONARY STATEMENTS
HIGHLY TOXIC (USA)
VERY TOXIC (EU)
VERY TOXIC BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
DANGER OF CUMULATIVE EFFECTS.
MAY CAUSE SENSITIZATION BY INHALATION AND SKIN CONTACT.
IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN.
TARGET ORGAN(S):
NERVES
KIDNEYS
KEEP AWAY FROM FOOD, DRINK AND ANIMAL FEEDINGSTUFFS.
AFTER CONTACT WITH SKIN, WASH IMMEDIATELY WITH PLENTY OF WATER.
IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF
WATER AND SEEK MEDICAL ADVICE.
WEAR SUITABLE PROTECTIVE CLOTHING.
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -
IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED
CLOTHING AND SHOES.
IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
CALL A PHYSICIAN IMMEDIATELY.
WASH CONTAMINATED CLOTHING BEFORE REUSE.
SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -
EXTINGUISHING MEDIA
WATER SPRAY.
CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.
SPECIAL FIREFIGHTING PROCEDURES
WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO
PREVENT CONTACT WITH SKIN AND EYES.
UNUSUAL FIRE AND EXPLOSIONS HAZARDS
EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
THIS MATERIAL, LIKE MOST MATERIALS IN POWDER FORM, IS CAPABLE OF
CREATING A DUST EXPLOSION.
SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -
EVACUATE AREA.
WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY
RUBBER GLOVES.
SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL.
AVOID RAISING DUST.
VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -
REFER TO SECTION 8.
SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -
WEAR APPROPRIATE NIOSH/MSHA-APPROVED RESPIRATOR, CHEMICAL-RESISTANT
GLOVES, SAFETY GOGGLES, OTHER PROTECTIVE CLOTHING.
SAFETY SHOWER AND EYE BATH.
USE ONLY IN A CHEMICAL FUME HOOD.
DO NOT BREATHE DUST.
DO NOT GET IN EYES, ON SKIN, ON CLOTHING.
AVOID PROLONGED OR REPEATED EXPOSURE.
WASH THOROUGHLY AFTER HANDLING.
KEEP TIGHTLY CLOSED.
STORE IN A COOL DRY PLACE.
SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -
APPEARANCE AND ODOR
WHITE POWDER
PHYSICAL PROPERTIES
MELTING POINT: 232 C TO 233 C (DEC)
SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -
STABILITY
STABLE.
INCOMPATIBILITIES
STRONG OXIDIZING AGENTS
STRONG ACIDS
STRONG BASES
MAY DISCOLOR ON EXPOSURE TO LIGHT.
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS
TOXIC FUMES OF:
CARBON MONOXIDE, CARBON DIOXIDE
SULFUR OXIDES
MERCURY/MERCURY OXIDES
SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -
ACUTE EFFECTS
MAY BE FATAL IF INHALED, SWALLOWED, OR ABSORBED THROUGH SKIN.
CAUSES EYE AND SKIN IRRITATION.
MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPER
RESPIRATORY TRACT.
MAY CAUSE ALLERGIC REACTION.
POSSIBLE ALLERGIC REACTION TO DUST IF INHALED, INGESTED OR IN CONTACT
WITH THE SKIN. HYPERSENSITIVITY REACTIONS MANIFESTED BY ERYTHEMA,
PAPULAR OR VESICULAR ERUPTIONS OCCUR OCCASIONALLY. ALLERGIC
CONJUNCTIVITIS HAS BEEN REPORTED.
TARGET ORGAN(S):
NERVES
KIDNEYS
TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND
TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.
RTECS #: OV8400000
MERCURY, ((O-CARBOXYPHENYL)THIO)ETHYL-, SODIUM SALT
IRRITATION DATA
EYE-RBT 8 UG MLD AJOPAA 78,98,1974
TOXICITY DATA
IAL-CHD LDLO:60 MG/KG/4W-I JOPDAB 104,311,1984
ORL-RAT LD50:75 MG/KG PCOC** -,1130,1966
SCU-RAT LD50:98 MG/KG CTOXAO 4,185,1971
UNR-RAT LD50:40 MG/KG 30ZDA9 -,290,1971
ORL-MUS LD50:91 MG/KG NYKZAU 58,235,1962
IPR-MUS LD50:54 MG/KG NYKZAU 58,235,1962
SCU-MUS LD50:66 MG/KG QJPPAL 12,212,1939
IVN-MUS LD50:45 MG/KG QJPPAL 12,212,1939
TARGET ORGAN DATA
BEHAVIORAL (ATAXIA)
BEHAVIORAL (COMA)
LUNGS, THORAX OR RESPIRATION (OTHER CHANGES)
GASTROINTESTINAL (NAUSEA OR VOMITING)
KIDNEY, URETER, BLADDER (CHANGES IN TUBULES)
EFFECTS ON FERTILITY (POST-IMPLANTATION MORTALITY)
EFFECTS ON FERTILITY (ABORTION)
EFFECTS ON EMBRYO OR FETUS (FETAL DEATH)
TUMORIGENIC EFFECTS (UTERINE TUMORS)
NUTRITIONAL AND GROSS METABOLIC (CHANGES IN: METABOLIC ACIDOSIS)
TUMORIGENIC (NEOPLASTIC BY RTECS CRITERIA)
TUMORIGENIC (TUMORS AT SITE OF APPLICATION)
ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
(RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR
COMPLETE INFORMATION.
SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -
DATA NOT YET AVAILABLE.
SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -
CONTACT A LICENSED PROFESSIONAL WASTE DISPOSAL SERVICE TO DISPOSE OF
THIS MATERIAL.
OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.
SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -
CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.
SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -
EUROPEAN INFORMATION
VERY TOXIC
R 26/27/28
VERY TOXIC BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
R 33
DANGER OF CUMULATIVE EFFECTS.
S 13
KEEP AWAY FROM FOOD, DRINK AND ANIMAL FEEDINGSTUFFS.
S 28
AFTER CONTACT WITH SKIN, WASH IMMEDIATELY WITH PLENTY OF WATER.
S 36
WEAR SUITABLE PROTECTIVE CLOTHING.
S 45
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
REVIEWS, STANDARDS, AND REGULATIONS
OEL=MAK
ACGIH TLV-TWA 0.1 MG(HG)/M3 (SKIN) DTLVS* TLV/BEI,1997
MSHA STANDARD-AIR:TWA 0.05 MG(HG)/M3
DTLWS* 3,22,1973
OSHA PEL (GEN INDU):8H TWA 0.01 MG(HG)/M3
CFRGBR 29,1910.1000,1994
OSHA PEL (CONSTRUC):8H TWA 0.01 MG(HG)/M3 (SKIN)
CFRGBR 29,1926.55,1994
OSHA PEL (SHIPYARD):8H TWA 0.01 MG(HG)/M3 (SKIN)
CFRGBR 29,1915.1000,1993
OSHA PEL (FED CONT):8H TWA 0.01 MG(HG)/M3 (SKIN)
CFRGBR 41,50-204.50,1994
OEL-AUSTRALIA:TWA 0.05 MG(HG)/M3;SKIN JAN 1993
OEL-BELGIUM:TWA 0.05 MG(HG)/M3;SKIN JAN 1993
OEL-DENMARK: TWA 0.05 MG(HG)/M3, SKIN, JAN1999
OEL-FINLAND:TWA 0.05 MG(HG)/M3 JAN 1993
OEL-JAPAN: OEL 0.05 MG(HG)/M3, JAN1999
OEL-GERMANY:TWA 0.01 PPM (0.1 MG(HG)/M3) JAN 1993
OEL-HUNGARY:TWA 0.02 MG(HG)/M3;STEL 0.04 MG(HG)/M3 JAN 1993
OEL-JAPAN:TWA 0.05 MG(HG)/M3 JAN 1993
OEL-POLAND: MAC(TWA) 0.05 MG(HG)/M3, MAC(STEL) 0.15 MG(HG)/M3, JAN1999
OEL-THE NETHERLANDS:TWA 0.05 MG(HG)/M3;STEL 0.15 MG(HG)/M3 JAN 1993
OEL-THE PHILIPPINES:TWA 0.05 MG(HG)/M3 JAN 1993
OEL-RUSSIA:TWA 0.05 MG(HG)/M3;STEL 0.01 MG(HG)/M3 JAN 1993
OEL-SWEDEN:TWA 0.05 MG(HG)/M3 JAN 1993
OEL-THAILAND:STEL 0.05 MG(HG)/M3 JAN 1993
OEL-UNITED KINGDOM:TWA 0.05 MG(HG)/M3;STEL 0.15 MG(HG)/M3 JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA CHECK ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM CHECK ACGIH TLV
NIOSH REL TO MERCURY, ARYL AND INORGANIC-AIR:CL 0.1 MG/M3 (SK)
NIOSH* DHHS #92-100,1992
NOHS 1974: HZD 84569; NIS 83; TNF 5617; NOS 30; TNE 242717
NOES 1983: HZD 84569; NIS 32; TNF 3695; NOS 41; TNE 152997; TFE 114190
EPA GENETOX PROGRAM 1988, POSITIVE: S CEREVISIAE GENE CONVERSION
EPA TSCA SECTION 8(B) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1999
U.S. INFORMATION
THIS PRODUCT IS SUBJECT TO SARA SECTION 313 REPORTING REQUIREMENTS -
MERCURY COMPOUNDS.
SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO
BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,
FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING
OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR
PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
COPYRIGHT 1998 SIGMA-ALDRICH CO.
LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY
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